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NCT07418671
Ultrasound Guided Lumbar Erector Spinae Block Using Bupivacaine - Magnesium Sulphate Versus Bupivacaine - Dexamethasone in Total Hip Replacement Surgery
Phase 2 trial testing Bupivacaine-Magnesium Sulphate in Post-operative Pain in 66 participants. Completed in 25 November 2025.
1 November 2025
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | supportive care |
| Enrollment | 66 |
| Start date | 1 May 2025 |
| Primary completion | 1 November 2025 |
| Estimated completion | 25 November 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Bupivacaine-Magnesium Sulphate
- Bupivacaine-Dexamethasone — full drug profile →
- Bupivacaine-Saline
Conditions studied
- Post-operative Pain — all drugs for Post-operative Pain →
- Total Hip Arthroplasty (THA) — all drugs for Total Hip Arthroplasty (THA) →
- Erector Spinae Plane Block — all drugs for Erector Spinae Plane Block →
Sponsor
Ain Shams University
Who can join
22 and older, any sex, with Post-operative Pain or Total Hip Arthroplasty (THA). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The current study was done to evaluate the effect of adding dexamethasone and magnesium sulfate to bupivacaine as adjuvants in an ultrasound-guided erector spinae block for patients undergoing total hip arthroplasty (THA), and to assess their impact on the timing of the first request for analgesia and on overall postoperative analgesic requirements.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07418671
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Ain Shams University trials
Trials by the same sponsor.
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- NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07418671 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 18 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07418671.
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