NCT07413562 (MARS-TBI) is a NA clinical trial of Median nerve stimulation in Traumatic Brain Injury, sponsored by Beijing Tiantan Hospital.

Who is sponsoring NCT07413562?

NCT07413562 is sponsored by Beijing Tiantan Hospital.

What drugs are being tested in NCT07413562?

Interventions in NCT07413562: Median nerve stimulation, Sham.

What condition does NCT07413562 study?

NCT07413562 studies Traumatic Brain Injury, Cognitive Dysfunction.

Is NCT07413562 still recruiting?

NCT07413562 is currently recruiting now. Last updated 17 February 2026.

Last reviewed 2026-02-17 · How we verify

NCT07413562: MARS-TBI

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Feasibility, Safety, and Preliminary Efficacy of Median Nerve Stimulation for Cognitive Dysfunction in Patients With Acute Traumatic Brain Injury

Recruiting now NA Last updated 17 February 2026

What this trial tests

NA trial testing Median nerve stimulation in Traumatic Brain Injury in 30 participants. Currently enrolling.

Timeline

1 February 2025

Primary endpoint
30 September 2026

31 December 2026

Quick facts

Lead sponsor	Beijing Tiantan Hospital
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	30
Start date	1 February 2025
Primary completion	30 September 2026
Estimated completion	31 December 2026
Sites	1 location across China

Drugs / interventions tested

Median nerve stimulation
Sham

Conditions studied

Traumatic Brain Injury — all drugs for Traumatic Brain Injury →
Cognitive Dysfunction — all drugs for Cognitive Dysfunction →

Sponsor

Beijing Tiantan Hospital

Who can join

Adults 18 to 64, any sex, with Traumatic Brain Injury or Cognitive Dysfunction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Currently, the treatment of cognitive dysfunction after acute TBI remains a challenge, and novel therapeutic methods are urgently needed. Median nerve stimulation (MNS) is a non-invasive neuromodulation technique and recently has shown positive effects in awaking coma of acute brain injury. It has been shown to improve cognition in healthy volunteers and may be a potential therapeutic approach for cognitive dysfunction in patients with acute TBI. Therefore, the main purpose of the study is to evaluate the feasibility, safety, and preliminary efficacy of MNS for cognitive dysfunction in patients with acute TBI.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Median nerve stimulation

Trials testing the same drug.

NCT06471244 — Development of Electroencephalography (EEG) and Magnetoencephalography (MEG) Source Reconstruction With Fast Multipole M · NA · recruiting
NCT05272202 — Investigation of Cerebral Motor Activity Modulations Following Median Nerve Stimulation During General Anaesthesia · EARLY_PHASE1 · recruiting

Other recruiting trials for Traumatic Brain Injury

Currently open trials in the same condition.

NCT07176936 — Improving Speech in Noise Using Noninvasive Stimulation · NA · recruiting
NCT07473505 — Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospect · recruiting
NCT07455136 — A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Mon · recruiting
NCT07404761 — Safety and Effectiveness of Spatial StimelMD (SSMD) in Subjects With Upper Limb Neuromotor Impairments · NA · recruiting
NCT07230002 — Effects of Moderate/Severe Traumatic Brain Injury in the Subacute or Chronic Phase on Locomotor Strategies Involved in N · NA · recruiting

Other Beijing Tiantan Hospital trials

Trials by the same sponsor.

NCT07341854 — Dexamethasone Palmitate for Postoperative Pain · NA · not yet recruiting
NCT07527013 — Stratified Blood Pressure Management Strategy After Endovascular Treatment for Acute Ischemic Stroke · Phase 3 · not yet recruiting
NCT07520370 — Effect of Perioperative Ulinastatin on Postoperative Stroke in Patients With Brain Tumor · NA · not yet recruiting
NCT07526987 — Efficacy and Safety of Minocycline in Patients With Acute Ischaemic Stroke Receiving Intravenous Thrombolysis · Phase 3 · not yet recruiting
NCT07591207 — The Efficacy and Safety of Loxoprofen Sodium Patch in Relieving Postoperative Pain After Laparoscopic Surgery · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07413562 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Beijing Tiantan Hospital
Last refreshed: 17 February 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07413562.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing