A Randomized, Vehicle-Controlled, Double-Masked, Parallel-Group Study to Evaluate the Use of Topical Ocular BL1332 for the Management of Postoperative Ocular Pain Following Photorefractive Keratectomy

NCT07412496 Phase 2 NOT_YET_RECRUITING

This is a multicenter, double-masked study to evaluate the use of Topical Ocular BL1332 for the management of post-operative pain after Photorefractive Keratectomy (PRK) surgery.

Details

Lead sponsor	Bausch & Lomb Incorporated
Phase	Phase 2
Status	NOT_YET_RECRUITING
Enrolment	123
Start date	2026-04
Completion	2027-02

Conditions

• Pain, Postoperative

Interventions

• Topical Ocular BL1332 low dose
• Topical Ocular BL1332 high dose
• BL1332 Vehicle ophthalmic vehicle

Primary outcomes

• Ocular pain intensity following PRK surgery — Assessed at a 24-hour period following PRK surgery
  Ocular pain intensity assessed using numeric pain rating scale 0 to 10, with 10 being the worst pain