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NCT07401407: APENERAS
RICA (ERAS) Pathway Adherence and Early Discharge Feasibility After Urgent Uncomplicated Appendectomy (APENERAS)
trial in Acute Appendicitis in 193 participants. Completed in 26 February 2025.
27 January 2025
Quick facts
| Lead sponsor | Hospital Galdakao-Usansolo |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 193 |
| Start date | 7 December 2022 |
| Primary completion | 27 January 2025 |
| Estimated completion | 26 February 2025 |
| Sites | 4 locations across Spain |
Conditions studied
- Acute Appendicitis — all drugs for Acute Appendicitis →
- Appendectomy — all drugs for Appendectomy →
- Ambulatory Surgery — all drugs for Ambulatory Surgery →
Sponsor
Hospital Galdakao-Usansolo
Who can join
Adults 18 to 75, any sex, with Acute Appendicitis or Appendectomy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This multicenter, prospective observational study (APENERAS) evaluates adherence to the RICA (ERAS Zaragoza 2022) perioperative care pathway in adults undergoing urgent laparoscopic appendectomy for uncomplicated acute appendicitis. The study aims to describe real-world adherence to the pathway across participating hospitals and to explore its association with patient safety and recovery outcomes. Key outcomes include postoperative complications (including severity), length of hospital stay, and readmissions within 30 days. Patient-reported satisfaction is also assessed using a structured survey. In addition, the study evaluates the feasibility of early discharge/ambulatory management by intention-to-treat, using a standardized checklist of clinical, functional, and social discharge criteria assessed during the first 24 hours after surgery. No changes to usual clinical care are introduced. Data are collected from routine perioperative management and follow-up.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07401407
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Acute Appendicitis
Currently open trials in the same condition.
- NCT07496723 — Comparison of Diagnostic Methods in Patients Operated for Suspected Appendicitis · recruiting
- NCT07008092 — Prostaglandin-E Urinary Metabolite (PGE-M) as a Predictor of Acute Appendicitis in Children · recruiting
- NCT07492329 — Antibiotics vs Surgery in Acute Appendicitis · NA · active not recruiting
- NCT06563349 — Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy · Phase 4 · recruiting
- NCT03236961 — Optimizing the Antibiotic Treatment of Uncomplicated Acute Appendicitis · NA · active not recruiting
Other Hospital Galdakao-Usansolo trials
Trials by the same sponsor.
- NCT05168722 — COVID-19, Patients' Evolution and the Influence of the Pandemic on Health Care and Outcomes in Chronic Diseases · completed
- NCT05574790 — Identification of Multimorbid Patients With a Higher Probability of Readmission and Mortality · completed
- NCT04188990 — Cost Effectiveness of an Intervention in Hospitalized Patients With Disease-related Malnutrition · NA · completed
- NCT04463706 — COVID19 Severity Prediction and Health Services Research Evaluation · completed
- NCT05247307 — Efficacy of the Infusion of Donor Plasma in COVID-19 Infection · Phase 3 · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07401407 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital Galdakao-Usansolo
- Last refreshed: 10 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07401407.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing