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NCT07400432: EXCOG
Acute Effects of Moderate-Intensity Continuous Exercise Versus HIIT on Cognitive Performance and Psychophysiological Responses in Physically Active Adults
NA trial testing Moderate-Intensity Continuous Exercise (MICE) in Sustained Attention in 38 participants. Enrolling by invitation.
1 March 2026
Quick facts
| Lead sponsor | Qassim University |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 38 |
| Start date | 1 October 2025 |
| Primary completion | 1 March 2026 |
| Estimated completion | 5 April 2026 |
| Sites | 1 location across Saudi Arabia |
Drugs / interventions tested
- Moderate-Intensity Continuous Exercise (MICE)
- High-Intensity Interval Training (HIIT)
Conditions studied
- Sustained Attention — all drugs for Sustained Attention →
- Cognitive Performance — all drugs for Cognitive Performance →
- Cognitive Performance During Physical Activity — all drugs for Cognitive Performance During Physical Activity →
Sponsor
Qassim University
Who can join
Adults 18 to 30, any sex, with Sustained Attention or Cognitive Performance. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to compare the immediate effects of two common types of exercise-moderate-intensity continuous exercise and high-intensity interval training (HIIT)-on attention, alertness, and physiological responses in physically active young adults. Attention and mental alertness are essential for learning, academic performance, and daily functioning. Previous research suggests that a single session of exercise can temporarily improve cognitive performance, but it is not clear whether moderate exercise or high-intensity interval exercise is more effective in producing these immediate benefits. In this study, participants will complete two supervised treadmill exercise sessions on separate days: one session of moderate-intensity continuous exercise and one session of high-intensity interval training. The order of the two exercise sessions will be randomized, and there will be a rest period of 48 to 72 hours between sessions. Before and immediately after each exercise session, participants will complete computerized cognitive tests that measure sustained attention and reaction time. Heart rate, oxygen saturation, perceived exertion, mood, and alertness will also be measured to evaluate physiological and psychological responses to exercise. By comparing the effects of these two exercise approaches within the same individuals, this study aims to identify which type of exercise leads to better immediate cognitive performance and favorable physiological responses. The findings may help guide exercise recommendations for improving attention, alertness, and overall mental performance in young adults.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07400432
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07400432 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Qassim University
- Last refreshed: 10 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07400432.
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