NCT07400133: NIHR GHRC MLTC

Assessing Feasibility of a Digital Health Intervention for Multiple Long-Term Condition Care in Primary Health Settings in India and Nepal

Not yet recruiting Last updated 10 February 2026

What this trial tests

trial testing Electronic Decision Support System (EDSS) in Diseases of the Circulatory System in 180 participants. Not yet recruiting.

Timeline

15 February 2026

Primary endpoint
15 May 2026

30 May 2026

Quick facts

Lead sponsor	Centre for Chronic Disease Control, India
Status	Not yet recruiting
Study type	OBSERVATIONAL
Enrollment	180
Start date	15 February 2026
Primary completion	15 May 2026
Estimated completion	30 May 2026
Sites	6 locations across Nepal, India

Drugs / interventions tested

• Electronic Decision Support System (EDSS)
• Assisted telemedicine
• Patient facing mobile app and Community champions (Care coordinators)

Conditions studied

• Diseases of the Circulatory System — all drugs for Diseases of the Circulatory System →
• Diseases of the Respiratory System — all drugs for Diseases of the Respiratory System →
• Endocrine, Nutritional and Metabolic Diseases — all drugs for Endocrine, Nutritional and Metabolic Diseases →
• Mental, Behavioral and Neurodevelopmental Disorders — all drugs for Mental, Behavioral and Neurodevelopmental Disorders →

Sponsor

Centre for Chronic Disease Control, India — full company profile →

Who can join

Adults 40 to 100, any sex, with Diseases of the Circulatory System or Diseases of the Respiratory System. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This observational, non-randomized, single-arm pilot study aims to assess the acceptability, feasibility, usability, and implementation fidelity of a co-designed multi-component digital health intervention to support the management of multiple long-term conditions (MLTCs) in Government primary health care settings. The study is conducted among adult patients with MLTCs attending rural primary health centres and the primary care providers (Medical officers and Staff Nurse) delivering services at these facilities in India and Nepal.

The intervention comprises an electronic decision support system (EDSS) to facilitate evidence-based clinical decision-making, assisted telemedicine model to enable timely specialist consultations, and a patient-facing mobile application-supported by community champions to enhance care coordination, self-management, and treatment adherence. Participants will engage with these components over a three month implementation period and will complete surveys and qualitative interviews, alongside routine supervision checklists and system-usage analytics, to generate implementation and usability data.

The study will be implemented across six rural primary health centres in Jodhpur (Rajasthan) and Anakapalli (Andhra Pradesh), India, and Kathmandu, Nepal, enrolling approximately 30 patients per site along with all participating health care providers. Findings from this pilot will inform refinement of the intervention, study tools, and implementation strategies, and will provide critical evidence on contextual adaptability to support the design of a subsequent cluster randomized controlled trial under the NIHR Global Health Research Centre for Multiple Long-Term Conditions.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.