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NCT07394842: HN-ORAL-RT
Longitudinal Oral Health Changes After Head and Neck Radiotherapy
trial in Head & Neck Cancer in 100 participants. Participants enrolled and being followed up; not accepting new ones.
1 February 2026
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 1 February 2025 |
| Primary completion | 1 February 2026 |
| Estimated completion | 25 April 2026 |
| Sites | 1 location across Egypt |
Conditions studied
- Head & Neck Cancer — all drugs for Head & Neck Cancer →
- Head & Neck Squamous Cell Carcinoma — all drugs for Head & Neck Squamous Cell Carcinoma →
- Periodontal Disease — all drugs for Periodontal Disease →
- Xerostomia — all drugs for Xerostomia →
Sponsor
Ain Shams University
Who can join
18 and older, any sex, with Head & Neck Cancer or Head & Neck Squamous Cell Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This prospective observational study evaluates how head and neck radiotherapy affects oral health over time. Patients with head and neck cancer undergoing standard radiotherapy are followed from before treatment through multiple post-treatment visits. Changes in periodontal health, dental status, salivary function, and patient-reported oral health quality of life are assessed. The study aims to better understand the long-term oral complications of radiotherapy and to support improved preventive and supportive dental care for cancer patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07394842
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Ain Shams University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07394842 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 6 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07394842.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing