Last reviewed · How we verify
NCT07388147: SAPPHIRE-MM
Exercise Therapy for Multiple Myeloma Patients
NA trial testing Orthopedic consultation and rehabilitation by excercise therapy in Multiple Myeloma Bone Lesions in 71 participants. Not yet recruiting.
31 March 2029
Quick facts
| Lead sponsor | University Hospital Heidelberg |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 71 |
| Start date | 1 March 2026 |
| Primary completion | 31 March 2029 |
| Estimated completion | 31 March 2029 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Orthopedic consultation and rehabilitation by excercise therapy
Conditions studied
- Multiple Myeloma Bone Lesions — all drugs for Multiple Myeloma Bone Lesions →
Sponsor
University Hospital Heidelberg
Who can join
Adults 18 to 75, any sex, with Multiple Myeloma Bone Lesions. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Physical exercise is an important supportive therapy for cancer patients, as it improves quality of life in general and might mitigate the side effects of drug treatment. For patients with multiple myeloma in particular, significantly less evidence on the effectiveness of exercise therapy is available due to the fact that this disease is associated with severe bone degradation which might affect bone stability. Advances in oncologic drug treatment have improved overall survival in multiple myeloma significantly. Therefore, there is an increased interest for recommendations on physical activity in this patient group. Due to uncertainties regarding safety and feasibility of exercise therapy in multiple myeloma, both patients and therapists often remain hesitant. Therefore, an orthopaedic outpatient clinic has been established at the Myeloma Center of Heidelberg University Hospital. Here, patients receive consultation on bone stability and individualized physical exercise plans. Based on the expertise gained at the orthopaedic outpatient clinic, the aim of this study is to establish and evaluate structural measures for improved rehabilitation in multiple myeloma and to integrate them into routine clinical care.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07388147
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Multiple Myeloma Bone Lesions
Currently open trials in the same condition.
- NCT07026799 — Feasibility, Safety and Effectivity of an Exercise Intervention for Newly Diagnosed Multiple Myeloma Patients During Ind · NA · active not recruiting
Other University Hospital Heidelberg trials
Trials by the same sponsor.
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- NCT06913010 — DV 100 as a Framework for the Hospital Incident Command System · recruiting
- NCT06764134 — Assessing Pancreatic Fistula Rates After Distal Pancreatectomy Using AEON Endostapler · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07388147 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital Heidelberg
- Last refreshed: 4 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07388147.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing