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NCT07386444: IMACT
Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy
NA trial testing Inspiratory muscle training in Early Stage Breast Carcinoma in 58 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | Ohio State University Comprehensive Cancer Center |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 58 |
| Start date | 16 February 2026 |
| Primary completion | 31 December 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Inspiratory muscle training
Conditions studied
- Early Stage Breast Carcinoma — all drugs for Early Stage Breast Carcinoma →
- Dyspnea — all drugs for Dyspnea →
Sponsor
Ohio State University Comprehensive Cancer Center
Who can join
18 and older, female only, with Early Stage Breast Carcinoma or Dyspnea. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical trial studies whether breathing exercises for the muscles that help with breathing air in, inspiratory muscle training (IMT), works to improve breathing muscle strength, shortness of breath, and physical activity levels in women who are receiving chemotherapy for early-stage breast cancer (BC). Cancer and/or treatments for BC can directly result in muscle wasting that involves breathing muscles, skeletal muscles or heart muscles. Pain, weakness, shortness of breath, and side effects of cancer treatment may lead to lower physical activity levels. IMT involves breathing exercises using a small hand-held device. The device makes it a little harder to breathe in, which may help strengthen breathing muscles. IMT may be an effective way to improve breathing muscle strength, shortness of breath, and physical activity levels in women who are receiving chemotherapy for early-stage BC.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07386444
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Inspiratory muscle training
Trials testing the same drug.
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- NCT07289958 — Effects of Respiratory Muscle Training in Post-bariatric Surgery Patients · NA · recruiting
- NCT07413718 — Inspiratory Muscle Training in Amiotrophyc Lateral Sclerosis · NA · recruiting
- NCT07104357 — The Effect of Inspiratory Muscle Training on Breathing Pattern and Functionality in Patients With Chronic Heart Failure. · NA · not yet recruiting
- NCT06521268 — Effects of Inspiratory Muscle Training on Lymphedema · NA · active not recruiting
Other recruiting trials for Early Stage Breast Carcinoma
Currently open trials in the same condition.
- NCT06876714 — ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathol · Phase 3 · recruiting
- NCT06113016 — Prevention of Frailty With Fisetin and Exercise in Breast Cancer Survivors · Phase 2 · recruiting
- NCT06387173 — Registry of Patients Undergoing Cryoablation for Early Stage Breast Cancer · active not recruiting
- NCT05368428 — Transcutaneous Electrical Nerve Stimulation in Chemotherapy Induced Peripheral Neuropathy in Patients With Stage I-III E · NA · recruiting
- NCT05417867 — Evaluating the Association Among Changes in Gut Microbiome, Fatigue, and Chemotherapy-Induced Nausea in Early Stage Brea · recruiting
Other Ohio State University Comprehensive Cancer Center trials
Trials by the same sponsor.
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- NCT07529483 — Endoscopic Ultrasound-Guided Chemoablation for the Treatment of Pancreatic Cysts · Phase 2 · not yet recruiting
- NCT07455513 — A Novel Tobacco Cessation Resource for Smokers With a Diagnosed or Suspected Thoracic Cancer · NA · not yet recruiting
- NCT07217990 — Neoadjuvant Complete Response Customized Treatment Approach for Definitive Management of Breast Cancer · Phase 1, PHASE2 · not yet recruiting
- NCT07503925 — THRIVE Study: Understanding How Oral Nicotine Pouches Affect Public Health · Phase 4 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07386444 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ohio State University Comprehensive Cancer Center
- Last refreshed: 6 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07386444.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing