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NCT07386210
Antihypertensive Effects of Rosmarinus Officinalis L. Infusion
NA trial testing Rosemary extract infusion in Hypertension Arterial in 54 participants. Completed in 29 August 2025.
28 August 2025
Quick facts
| Lead sponsor | awatef Sassi |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 54 |
| Start date | 20 March 2023 |
| Primary completion | 28 August 2025 |
| Estimated completion | 29 August 2025 |
| Sites | 2 locations across Tunisia |
Drugs / interventions tested
- Rosemary extract infusion
- Placebo
Conditions studied
- Hypertension Arterial — all drugs for Hypertension Arterial →
Sponsor
awatef Sassi
Who can join
Adults 18 to 65, male only, with Hypertension Arterial. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study assessed the antihypertensive effect of rosemary tea through a placebo-controlled clinical study, angiotensin-converting enzyme (ACE) inhibition analysis, and in silico evaluation of interactions between rosemary bioactive compounds and the AT1R (Angiotensin II Type 1 Receptor). A randomized, double-blind, placebo-controlled trial was conducted in 54 male patients with mild hypertension. Participants were assigned to receive either rosemary infusion (n = 27) or placebo (n = 23) for 45 days. Ambulatory blood pressure monitoring wass used to evaluate blood pressure parameters. Serum ACE activity was measured at baseline and after the intervention using FAPGG hydrolysis. Molecular docking simulations were performed using the Dock 4.2 software.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07386210
- Europe PMC full search
- ASCO Meeting Library
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- bioRxiv preprints
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Related trials
Other recruiting trials for Hypertension Arterial
Currently open trials in the same condition.
- NCT05942729 — Etiological DiagnOsis of caRdiac Diseases Based on echoCardiograpHIc Images and Clinical Data. · recruiting
Other awatef Sassi trials
Trials by the same sponsor.
- NCT07352124 — Rosemary Infusion for Hypertension With Hypertriglyceridemia · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07386210 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by awatef Sassi
- Last refreshed: 4 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07386210.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing