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NCT07385300
Omega-3 Pufa and Aspirin as Adjunctive Therapy in Treatment of Smoker Patients With Stage Iii Periodontitis
NA trial testing Omega-3 PUFA and Aspirin as adjunctive therapy to (SRP) in Periodontitis in 45 participants. Completed in 22 August 2024.
22 August 2024
Quick facts
| Lead sponsor | Alexandria University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 45 |
| Start date | 20 August 2023 |
| Primary completion | 22 August 2024 |
| Estimated completion | 22 August 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Omega-3 PUFA and Aspirin as adjunctive therapy to (SRP)
- Omega-3 PUFA and Aspirin and doxycycline as adjunctive therapy to (SRP)
- scaling and root planning (SRP)
Conditions studied
- Periodontitis — all drugs for Periodontitis →
- Diabete Mellitus — all drugs for Diabete Mellitus →
Sponsor
Alexandria University
Who can join
35 and older, any sex, with Periodontitis or Diabete Mellitus. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: Smoking reduces the effect of non-surgical periodontal therapy, a host modulation regimen consisting of omega-3 polyunsaturated fatty acids (ω-3 PUFA) supplementation with low-dose aspirin (ASA) with or without systemic doxycycline has been proposed to improve treatment response. The Aim of the study is to explore the clinical effects of orally administered omega-3 PUFA and ASA with or without systemic doxycycline with periodontal debridement in treatment of smoker individuals with stage III periodontitis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07385300
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07385300 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Alexandria University
- Last refreshed: 4 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07385300.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing