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NCT07380685: Nurse-AI-CARE
On-Demand AI Support Via LINE-Based GPT Assistant to Improve Emotional Resilience and Reduce Burnout Among Clinical Nurses
NA trial testing Interactive LINE GPT Emotional Support in Occupational Stress and Mental Health in Clinical Nurses in 120 participants. Not yet recruiting.
28 June 2026
Quick facts
| Lead sponsor | Taipei Medical University Shuang Ho Hospital |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 120 |
| Start date | 1 May 2026 |
| Primary completion | 28 June 2026 |
| Estimated completion | 25 September 2026 |
Drugs / interventions tested
- Interactive LINE GPT Emotional Support
- Static Supportive Messages
Conditions studied
- Occupational Stress and Mental Health in Clinical Nurses — all drugs for Occupational Stress and Mental Health in Clinical Nurses →
- Burnout — all drugs for Burnout →
- Compassion Fatigue — all drugs for Compassion Fatigue →
- Psychological Resilience — all drugs for Psychological Resilience →
Sponsor
Taipei Medical University Shuang Ho Hospital
Who can join
Adults 20 to 65, any sex, with Occupational Stress and Mental Health in Clinical Nurses or Burnout. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Clinical nurses are frequently exposed to high emotional demands due to heavy workloads, time pressure, patient suffering, and the interpersonal complexity of clinical care. These stressors may contribute to compassion fatigue, burnout, reduced resilience, and decreased occupational well-being. However, timely and accessible psychological support is often limited in busy clinical environments, and many nurses may hesitate to seek help due to stigma, time constraints, or limited resources. This study is a prospective, randomized, controlled, parallel-group interventional trial designed to evaluate the feasibility and effectiveness of an on-demand, human-centered emotional support intervention delivered through a LINE-based GPT assistant. The AI assistant provides real-time supportive conversations, reflective prompts, stress-coping guidance, and resilience-enhancing strategies tailored specifically for clinical nurses, offering a private and easily accessible support resource. Eligible clinical nurses (target sample size: 100-120) are randomly assigned to either an Intervention Group, which interacts with the AI assistant, or a Control Group, which receives non-interactive static messages, over a four-week intervention period. Primary outcomes include changes in compassion fatigue, burnout, and compassion satisfaction, as measured by the Professional Quality of Life Scale (ProQOL). Secondary outcomes include changes in resilience (Brief Resilience Scale), general self-efficacy (General Self-Efficacy Scale), and perceived stress (Perceived Stress Scale-10). The results of this study are expected to provide evidence on the feasibility and potential effectiveness of AI-based emotional support as a scalable and accessible tool to promote psychological well-being among clinical nurses, thereby informing future digital mental health interventions in healthcare settings.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07380685 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Taipei Medical University Shuang Ho Hospital
- Last refreshed: 11 March 2026
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