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NCT07373899

Comparison of the Effect of Surgical Resection Based on Lesion Extent Before and After Neoadjuvant Therapy in Patients With Stage II-IIIB Non-Small Cell Lung Cancer: A Single-Center, Real-World, Open-Label Study.

Not yet recruiting Last updated 28 January 2026
What this trial tests

trial in Carcinoma, Non-Small-Cell Lung in 354 participants. Not yet recruiting.

Timeline
1 January 2026
Primary endpoint
31 December 2030
31 December 2030

Quick facts

Lead sponsorCancer Institute and Hospital, Chinese Academy of Medical Sciences
StatusNot yet recruiting
Study typeOBSERVATIONAL
Enrollment354
Start date1 January 2026
Primary completion31 December 2030
Estimated completion31 December 2030

Conditions studied

Sponsor

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Who can join

Eligibility, any sex, with Carcinoma, Non-Small-Cell Lung or Neoadjuvant Immunotherapy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study intends to conduct a prospective, non-interventional study to compare the survival benefits of different surgical resection patterns for patients with non-small cell lung cancer who have achieved partial response (PR) after immunotherapy induction. The study plans to enroll patients suitable for surgery as assessed by radiomics evaluation and multidisciplinary team (MDT) discussion, and will assign them to the modified surgery group and the conventional surgery group based on patient preference. The resection scope in the modified surgery group is more limited compared to conventional surgery, aiming to maximize preservation of pulmonary function while ensuring oncological safety. This study will systematically evaluate the impact of different resection scopes on patient prognosis after neoadjuvant immunotherapy, providing clinical evidence for exploring individualized surgical strategies for non-small cell lung cancer in the era of immunotherapy.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Carcinoma, Non-Small-Cell Lung

Currently open trials in the same condition.

Other Cancer Institute and Hospital, Chinese Academy of Medical Sciences trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07373899.

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