Last reviewed · How we verify
NCT07373288: HOGWARTS
HOXB7 and Linked Tissue and Blood Biomarkers in the Lungs of Patients With Pulmonary Fibrosis
trial testing Biopsy in Fibrosis, Pulmonary in 80 participants. Currently enrolling.
1 July 2027
Quick facts
| Lead sponsor | University of Modena and Reggio Emilia |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 80 |
| Start date | 1 July 2023 |
| Primary completion | 1 July 2027 |
| Estimated completion | 1 July 2030 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Biopsy — full drug profile →
Conditions studied
- Fibrosis, Pulmonary — all drugs for Fibrosis, Pulmonary →
Sponsor
University of Modena and Reggio Emilia
Who can join
Adults 18 to 80, any sex, with Fibrosis, Pulmonary. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This pilot, multicenter, interventional study investigates the expression of HOXB7 and its associated molecular pathway in lung tissue and blood-derived exosomes from patients with pulmonary fibrosis (PF), including idiopathic pulmonary fibrosis (IPF). Using RNA sequencing (RNA-Seq) and proteomic analysis via mass spectrometry (MS), the study aims to identify tissue and circulating biomarkers associated with fibrosis progression. The study compares different biopsy techniques (surgical vs. transbronchial cryobiopsy) and also includes a control group of patients undergoing lung resection for non-fibrotic conditions.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07373288
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Biopsy
Trials testing the same drug.
- NCT06675123 — Pacritinib in Combination With a BTK Inhibitor for the Treatment of Patients With Relapsed or Refractory Mantle Cell Lym · Phase 1 · recruiting
- NCT06670976 — Propranolol Plus Standard Radiation Therapy Before Surgery for the Treatment of Patients With Soft Tissue Sarcoma · Phase 1 · withdrawn
- NCT07217990 — Neoadjuvant Complete Response Customized Treatment Approach for Definitive Management of Breast Cancer · Phase 1, PHASE2 · not yet recruiting
- NCT06860815 — Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Br · Phase 2 · recruiting
- NCT05741164 — Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory · Phase 2 · not yet recruiting
Other recruiting trials for Fibrosis, Pulmonary
Currently open trials in the same condition.
- NCT06527612 — The Effect of Exercise Training on Quality of Life and Disease Progression in Fibrosing Interstitial Lung Patients · NA · recruiting
- NCT05310669 — Inspiratory Effort Assessed Through Nasal Pressure Measurement in Patients With Idiopathic Pulmonary Fibrosis · recruiting
- NCT06815185 — Rehabilitation Counselling for Patients with Interstitial Lung Disease · recruiting
Other University of Modena and Reggio Emilia trials
Trials by the same sponsor.
- NCT05282238 — Quantification of Inspiratory Effort Through Nasal Pressure in Patients Undergoing Weaning From Invasive Mechanical Vent · not yet recruiting
- NCT07404423 — OPEN-IPF: Observational Prediction modEl for cliNical Outcomes in Idiopathic Pulmonary Fibrosis · not yet recruiting
- NCT06989385 — CORALINE - Correlation Between Physiological and Clinical Variables and Failure of Non-Invasive Respiratory Support in P · recruiting
- NCT06734949 — CoMPaSS-NMD - Computational Models for New Patients Stratification Strategies of HNMD · enrolling by invitation
- NCT05043753 — "Fetal gRowth AbnorMality dEtection Trial" · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07373288 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Modena and Reggio Emilia
- Last refreshed: 4 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07373288.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing