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NCT07364838
Study to Evaluate the Effect of Food on the Pharmacokinetics and Pharmacodynamics Characteristics in Healthy Adult Volunteers
Phase 1 trial testing DW4421 in GERD (Gastroesophageal Reflux Disease) in 24 participants. Completed in 8 April 2025.
8 April 2025
Quick facts
| Lead sponsor | Daewon Pharmaceutical Co., Ltd. |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 24 |
| Start date | 21 November 2024 |
| Primary completion | 8 April 2025 |
| Estimated completion | 8 April 2025 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- DW4421 — full drug profile →
Conditions studied
- GERD (Gastroesophageal Reflux Disease) — all drugs for GERD (Gastroesophageal Reflux Disease) →
Sponsor
Daewon Pharmaceutical Co., Ltd. — full company profile →
Who can join
Adults 19 to 50, any sex, with GERD (Gastroesophageal Reflux Disease). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A Randomized, Open-label, Oral in healthy volunteers
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07364838
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of DW4421
Trials testing the same drug.
- NCT07364877 — A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetics of DW4421 and DW4421S in Healthy Adult Volunteers · Phase 1 · enrolling by invitation
- NCT07343245 — A Phase 1 Clinical Trial to Evaluate the Safety and DDI of DW4421 and 3 NSAIDs · Phase 1 · recruiting
Other recruiting trials for GERD (Gastroesophageal Reflux Disease)
Currently open trials in the same condition.
- NCT07252180 — Comparing Two Different Methods of Ablation of Inlet Patches (APC vs RFA) · NA · active not recruiting
- NCT07125521 — Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of the Smartphone Applicat · NA · recruiting
- NCT07121803 — The Influence of Specialized Food Products Based on Ice-Cream on Esophageal Motility · NA · recruiting
- NCT06928350 — Normal Values of Ambulatory 24-hour Oesophageal pH-impedance Monitoring in an Indian Cohort of Participants · recruiting
- NCT07252115 — TLSA Versus TBSA Surgical Approach for Hiatal Hernia With Gastroesophageal Reflux Disease · NA · recruiting
Other Daewon Pharmaceutical Co., Ltd. trials
Trials by the same sponsor.
- NCT07364851 — A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetics of DW4421-T1 and DW4421S-T1 in Healthy Adult Volunt · Phase 1 · not yet recruiting
- NCT07349589 — Evaluate the Safety, Tolerability and Pharmacokinetics of DW5524 in Healthy Adult Volunteers · Phase 1 · not yet recruiting
- NCT07364877 — A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetics of DW4421 and DW4421S in Healthy Adult Volunteers · Phase 1 · enrolling by invitation
- NCT07343245 — A Phase 1 Clinical Trial to Evaluate the Safety and DDI of DW4421 and 3 NSAIDs · Phase 1 · recruiting
- NCT07319559 — Clinical Trial to Evaluate the Safety, Pharmacokinetic Characteristics of DW5124 and DW5124-R, and the Effect of Food on · Phase 1 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07364838 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Daewon Pharmaceutical Co., Ltd.
- Last refreshed: 23 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07364838.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing