Prevention of Hypotension During Elective Cesarean Section Under Spinal Anaesthesia With Fixed-rate Metaraminol Infusion Versus Fixed-rate Norepinephrine Infusion: A Double-blind Randomised Controlled Clinical Trial.

NCT07363109 NA NOT_YET_RECRUITING

The aim of this double-blind randomised study will be to compare a fixed-rate prophylactic metaraminol infusion to a fixed-rate prophylactic norepinephrine infusion during elective cesarean section under combined spinal-epidural anaesthesia.

Details

Lead sponsor	Aretaieion University Hospital
Phase	NA
Status	NOT_YET_RECRUITING
Enrolment	80
Start date	2026-02
Completion	2029-03

Conditions

• Hypotension After Spinal Anesthesia
• Hypotension During Cesarean Delivery

Interventions

• Metaraminol infusion
• Norepinephrine infusion

Primary outcomes

• incidence of hypotension — intraoperative
  any occurrence of hypotension throughout the operation will be recorded (SAP \< 80% of baseline)
• number of hypotensive episodes in the pregnant woman — intraoperativre
  the number of hypotensive episodes (SAP \< 80% of baseline)throughout the operation will be recorded
• incidence of bradycardia — intraoperative
  any incidence of HR \< 60/min will be recorded