Last reviewed · How we verify

NCT07359287: GRASP

Impact of a Multimodal Intervention on Antibiotic Prescribing for Respiratory Infections in Primary Care

Recruiting now NA Last updated 22 January 2026
What this trial tests

NA trial testing Antibiotic prescribing according to guidelines in Angina in 4,500 participants. Currently enrolling.

Timeline
1 December 2025
Primary endpoint
1 June 2026
1 September 2026

Quick facts

Lead sponsorUniversity Hospital, Caen
PhaseNA
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposehealth services research
Enrollment4,500
Start date1 December 2025
Primary completion1 June 2026
Estimated completion1 September 2026
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Caen

Who can join

Eligibility, any sex, with Angina or Acute Bronchiolitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Antimicrobial resistance (AMR), considered one of the greatest global threats by the WHO, justifies the development of initiatives to promote appropriate antibiotic use-especially in primary care, where most antibiotics in France are prescribed and where misuse remains common. We are proposing a cluster-randomized controlled trial to evaluate the effectiveness of a bimodal intervention combining: (1) improved communication about the circulation of respiratory viruses, and (2) strengthened collaborative practices between general practitioners and pharmacists through a multidisciplinary protocol aimed at verifying that prescribed treatment durations comply with guidelines. The study will include six primary care practices (24 physicians), with three practices in each study arm. The aim of this project is to assess whether the bimodal intervention can reduce the duration of antibiotic treatments for upper and lower respiratory tract infections. The first component (a "viral infection prescription" tool) focuses on reducing unnecessary treatment initiation, while the second (pharmacist-led review) aims to shorten excessive prescription durations.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Angina

Currently open trials in the same condition.

Other University Hospital, Caen trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07359287.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing