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NCT07352215: PRPLT
PRP Plus Fractional CO₂ Laser for Acne Scars
NA trial testing Fractional CO₂ Laser + Platelet-Rich Plasma (PRP) in Post-Acne Atrophic Scars in 70 participants. Currently enrolling.
12 January 2026
Quick facts
| Lead sponsor | Gujranwala medical college District Headquarters Hospital, Gujranwala |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 70 |
| Start date | 31 October 2025 |
| Primary completion | 12 January 2026 |
| Estimated completion | 30 April 2026 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Fractional CO₂ Laser + Platelet-Rich Plasma (PRP)
- Fractional CO₂ Laser Only
Conditions studied
- Post-Acne Atrophic Scars — all drugs for Post-Acne Atrophic Scars →
- Carbon Dioxide Lasers — all drugs for Carbon Dioxide Lasers →
- Platelet-Rich Plasma — all drugs for Platelet-Rich Plasma →
Sponsor
Gujranwala medical college District Headquarters Hospital, Gujranwala
Who can join
Adults 18 to 40, any sex, with Post-Acne Atrophic Scars or Carbon Dioxide Lasers. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized controlled trial aims to evaluate whether adding platelet-rich plasma (PRP) to fractional CO₂ laser resurfacing improves the treatment of moderate-to-severe acne scars compared with laser alone. Seventy adults aged 18-40 years will be recruited from the Dermatology Department of Gujranwala Medical College Teaching Hospital. Participants will be randomly assigned to receive either fractional CO₂ laser combined with topical PRP or fractional CO₂ laser alone, with three treatment sessions delivered four weeks apart. The primary outcome is the change in acne scar severity measured using the Goodman and Baron Quantitative Acne Scar Scale. Secondary outcomes include redness, edema, pain scores, and patient satisfaction assessed using Likert and numeric rating scales. The study is single-blinded, with patients unaware of treatment allocation. PRP will be prepared using a standardized double-spin centrifugation process. Data will be analyzed using appropriate statistical tests with a significance level of p \< 0.05. The study aims to determine whether PRP enhances laser efficacy, reduces side effects, and improves patient-reported outcomes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07352215
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
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Other Gujranwala medical college District Headquarters Hospital, Gujranwala trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07352215 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Gujranwala medical college District Headquarters Hospital, Gujranwala
- Last refreshed: 20 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07352215.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing