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Intensive Versus Conventional Blood Pressure Control Following Stroke Thrombectomy (INTENSE)
This clinical trial aims to investigate the safety and efficacy of intensive blood pressure lowering after successful reperfusion with thrombectomy in patients with acute anterior circulation large artery occlusive stroke. The main questions it aims to answer are: What is the optimal blood pressure range after revascularization with thrombectomy in patients with cerebral embolism? Can intensive blood pressure lowering improve outcomes in cerebral embolism patients following thrombectomy? Participants will be randomly assigned to either the intervention group, which receives stricter blood pressure control (systolic blood pressure target \<120 mmHg), or the control group, which follows a conventional blood pressure management approach (systolic blood pressure target 140-180 mmHg). Outcomes will be assessed during a 3-month follow-up period.
Details
| Lead sponsor | Hao Yonggang |
|---|---|
| Phase | NA |
| Status | RECRUITING |
| Enrolment | 910 |
| Start date | Sat Nov 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sun Dec 31 2028 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Stroke
Interventions
- Intensive blood pressure management
- Conventional blood pressure management
Countries
China