Last reviewed · How we verify
NCT07348770
Cold Plasma Effects on Dental Implant Stability
NA trial testing Dental implant placement in Cold Atmospheric Plasma in 11 participants. Completed in 9 September 2025.
8 July 2025
Quick facts
| Lead sponsor | Kahramanmaras Sutcu Imam University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 11 |
| Start date | 24 February 2025 |
| Primary completion | 8 July 2025 |
| Estimated completion | 9 September 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Dental implant placement
- Dental implant placement and vacuum plasma application
- Dental implant placement and argon jet plasma application
- Dental implant placement and cold atmospheric plasma application
Conditions studied
- Cold Atmospheric Plasma — all drugs for Cold Atmospheric Plasma →
- Dental Implants — all drugs for Dental Implants →
Sponsor
Kahramanmaras Sutcu Imam University
Who can join
18 and older, any sex, with Cold Atmospheric Plasma or Dental Implants. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cold plasma-mediated implant surface activation may reverse the biological aging of titanium by enhancing hydrophilicity and cellular response. The aim of this study was to clinically compare the effects of three different cold plasma systems on the stability of dental implants. In this prospective randomized controlled split-mouth study, a total of 44 implants were placed in 11 patients. In each patient, four implants were randomly allocated to one of the following groups: control, vacuum plasma, argon jet plasma, and cold atmospheric plasma. All implants were placed using a single-stage protocol with a minimum insertion torque of 45 Ncm. Implant stability was assessed using resonance frequency analysis (ISQ values) immediately after placement and at 2, 4, and 8 weeks.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Clinical evaluation of cold plasma surface activation using different plasma systems on early implant stability: a randomized controlled within-patient trial.
Balkanlıoğlu AC, Acikan I. · · 2026 · PMID 42226275 · DOI 10.1186/s12903-026-08679-8
Verify or expand the search:
- PubMed search for NCT07348770
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Dental implant placement
Trials testing the same drug.
- NCT07534787 — Clinical and Radiographic Evaluation of Ridge Splitting With Simultaneous Implant Placement Covered With Concentrated Gr · NA · not yet recruiting
- NCT07104370 — Freeze-dried Bone Allograft vs Autologous Bone Blocks in the Lateral Augmentation of the Jaws · NA · recruiting
- NCT07082244 — Implant Phenotype Modification Via GBR and ADM · NA · recruiting
- NCT06764654 — Randomized Clinical Study Comparing Two Guided Surgery Techniques for Free-end Implant Placement · NA · recruiting
- NCT06417788 — Dynamic Guided Implant Surgery VS Static Guided Surgery. · NA · recruiting
Other Kahramanmaras Sutcu Imam University trials
Trials by the same sponsor.
- NCT07511322 — Enteral Nutrition Education Provided Using the Pecha Kucha Method · enrolling by invitation
- NCT07515287 — Restoration of Sensorimotor Function in Middle-Aged Women With Chronic Lumbar Disc Herniation: The Effect of Pilates on · NA · enrolling by invitation
- NCT07451691 — The Effect of the World Health Organisation-Based Intrapartum Care Model on Labour Pain, Comfort, Satisfaction and Postp · NA · not yet recruiting
- NCT07471412 — Sexually Transmitted Infections in Migrant Women · NA · not yet recruiting
- NCT07332065 — The Effects of Mandala Coloring on Women During Menopause · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07348770 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kahramanmaras Sutcu Imam University
- Last refreshed: 16 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07348770.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing