Last reviewed · How we verify
NCT07344168
EndoArt® Implantation in Subjects With Chronic Corneal Edema - US Study
NA trial testing The EndoArt® (Corneal Artificial Endothelial layer) in Corneal Edema in 123 participants. Not yet recruiting.
30 April 2029
Quick facts
| Lead sponsor | Eye-yon Medical |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 123 |
| Start date | 1 May 2026 |
| Primary completion | 30 April 2029 |
| Estimated completion | 30 April 2030 |
Drugs / interventions tested
- The EndoArt® (Corneal Artificial Endothelial layer)
Conditions studied
- Corneal Edema — all drugs for Corneal Edema →
Sponsor
Eye-yon Medical — full company profile →
Who can join
Adults 35 to 85, any sex, with Corneal Edema. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The EndoArt® device is intended to treat patients with chronic corneal edema due to endothelial dysfunction, in whom prior multiple keratoplasty (EK/PK) have failed, and who are not reasonable candidates for any form of corneal transplant, including penetrating keratoplasty. The EndoArt® (Corneal Artificial Endothelial layer) is a permanent synthetic implant. It is made of a clear, transparent, foldable, biologically compatible hydrophilic copolymer. The device serves as an inert physical barrier, blocking the ingress of fluid from the Anterior Chamber (AC) into the cornea.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07344168
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Corneal Edema
Currently open trials in the same condition.
- NCT06261346 — Plasma Rich in Growth Factors in Corneal Endothelial Transplantation · NA · recruiting
- NCT06983652 — Validation of the Use of Terahertz Scanning System on Corneal Scars and Corneal Edema · recruiting
- NCT05636579 — Study to Assess Safety and Tolerability of Multiple Doses of EO2002 · Phase 1 · recruiting
- NCT05436665 — The Belgian Endothelial Surgical Transplant of the Cornea · NA · recruiting
Other Eye-yon Medical trials
Trials by the same sponsor.
- NCT05139771 — EndoArt® Implantation in Subjects With Chronic Corneal Edema · NA · completed
- NCT03845374 — Prospective, Randomized Multi-Center Study of Using the Hyper-CL™ Lens in Subjects Suffering From Bacterial Keratitis · NA · completed
- NCT03069521 — Study to Evaluate the Safety of the EndoArt™ for Treatment of Subjects Suffering From Corneal Edema · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07344168 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Eye-yon Medical
- Last refreshed: 13 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07344168.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing