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NCT07342582
Identifying the Burden of Hospitalization Due to Rhinovirus (RV) in Children and Mechanisms of Pathogenesis Using Airway Molecular Profiling
trial testing Nasal Swab Healthy Surveillance in Rhinovirus in 670 participants. Not yet recruiting.
1 May 2030
Quick facts
| Lead sponsor | University of Wisconsin, Madison |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 670 |
| Start date | 1 May 2026 |
| Primary completion | 1 May 2030 |
| Estimated completion | 1 May 2030 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Nasal Swab Healthy Surveillance
- Nasal Swab Sick Samples
- Nasal Swab Hospitalized Cohort
- Sick Follow-up Survey
- Older Cohort Control Group
Conditions studied
- Rhinovirus — all drugs for Rhinovirus →
Sponsor
University of Wisconsin, Madison
Who can join
Under 17, any sex, with Rhinovirus. Healthy volunteers can join.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Aim 1: Summary of Rhinovirus Types Identified in Community Cohort
Time frame: data collected up to 36 months
To test study hypotheses, the study team will identify the circulating RV types in symptomatic and asymptomatic children. -
Aim 1: Unique Nasal Transcriptomic Signature of Clinical Rhinovirus Infections
Time frame: data collected up to 36 months
Sponsor's own description
The goal of this study is to determine the burden of Rhinoviruses (RVs) as a cause of acute, severe, respiratory illnesses leading to hospitalization. A community cohort of 120 children between 12 and 36 months of age will be enrolled in the first year of the study and followed (when well and sick) for 36 months to identify the circulating RVs and provide samples to establish a host nasal transcriptome differentiating clinical from subclinical RV infections. A hospitalized cohort of 450 infants and children will be enrolled during years 1 through 3 of the study and followed for the duration of their hospitalization to investigate the findings of the community cohort. An additional 100 healthy children aged 5-17 years will be enrolled for age-match comparison with the older hospitalized cohort.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07342582
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Rhinovirus
Currently open trials in the same condition.
- NCT07399132 — A Study of APL-10456-Vaccine · EARLY_PHASE1 · recruiting
- NCT07358910 — Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective · recruiting
Other University of Wisconsin, Madison trials
Trials by the same sponsor.
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- NCT07475104 — Redesigning Surgical Care for Patients in Wisconsin · NA · enrolling by invitation
- NCT07470723 — The ORIGIN-FH Study · NA · recruiting
- NCT06975657 — Well-being Skills for Reentry · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07342582 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Wisconsin, Madison
- Last refreshed: 23 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07342582.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing