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NCT07342075: DZM-CSVD-R
Registry Study of Cerebral Small Vessel Disease
trial in Cerebral Small Vessel Diseases in 50 participants. Currently enrolling.
31 August 2026
Quick facts
| Lead sponsor | Dongzhimen Hospital, Beijing |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 13 November 2025 |
| Primary completion | 31 August 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across China |
Conditions studied
- Cerebral Small Vessel Diseases — all drugs for Cerebral Small Vessel Diseases →
- Cognitive Impairment — all drugs for Cognitive Impairment →
- Diffusion Tensor Imaging — all drugs for Diffusion Tensor Imaging →
Sponsor
Dongzhimen Hospital, Beijing
Who can join
50 and older, any sex, with Cerebral Small Vessel Diseases or Cognitive Impairment. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The incidence of cerebral small vessel disease (CSVD) increases with age, affecting approximately 5% of individuals over 50 years old and nearly all individuals over 90 years old. CSVD is also the most important vascular factor contributing to cognitive decline, with 45% of dementia patients attributed to CSVD. Existing interventions are similar to secondary prevention strategies for cardiovascular and cerebrovascular diseases, and no specific therapies are currently available. CSVD-related cognitive impairment (CSVDCI) predominantly involves attention, processing speed, and executive functions, with relatively preserved memory function, and may be accompanied by non-cognitive clinical manifestations such as gait disturbances, emotional and behavioral disorders, and bladder dysfunction. Although CSVDCI can be classified under vascular cognitive impairment (VCI), there are certain differences in its clinical manifestations. In summary, it is necessary to develop more targeted treatments for CSVD. We attempt to establish a "symptom-tongue coating-gut microbiota-imaging" system to provide data support for the subsequent exploration of CSVD treatments based on traditional Chinese medicine (TCM) syndrome differentiation and treatment.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07342075
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Cerebral Small Vessel Diseases
Currently open trials in the same condition.
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- NCT06431711 — Fundus Optical coheRence Tomography Angiography Evaluation for Small-vessel Health in Cerebral Small Vessel Disease · recruiting
- NCT06164262 — Dementia Risk Registry for Young and Middle-aged CSVD Patients in the Next 10 Years · recruiting
- NCT06010511 — WHIte MAtter Hyperintensity Shape and Glymphatics · recruiting
Other Dongzhimen Hospital, Beijing trials
Trials by the same sponsor.
- NCT07271732 — Songling Xuemaikang Capsules for Cerebral Small Vessel Disease · NA · not yet recruiting
- NCT07163702 — Efficacy and Safety of Xinglou Chengqi Granule for Acute Ischemic Stroke · Phase 2 · not yet recruiting
- NCT06857487 — Qingre Huatan Formula for the Prevention of Early Neurological Deterioration in Acute Ischemic Stroke · Phase 1, PHASE2 · recruiting
- NCT06933238 — Efficacy of Fuzheng Tongfu Jiedu Prescription for Treating Gastrointestinal Dysfunction Associated With Sepsis · Phase 1, PHASE2 · not yet recruiting
- NCT06686355 — The Treatment of Sepsis Induced Myocardial Dysfunction With Yiqilishui Formula · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07342075 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dongzhimen Hospital, Beijing
- Last refreshed: 15 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07342075.
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