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NCT07339410
Physiotherapy to Improve Balance and Walking Capacity in Hemophilia
NA trial testing Physiotherapy in Hemophilia in 35 participants. Completed in 5 January 2026.
20 December 2025
Quick facts
| Lead sponsor | Yuzuncu Yil University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 35 |
| Start date | 20 October 2025 |
| Primary completion | 20 December 2025 |
| Estimated completion | 5 January 2026 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Physiotherapy — full drug profile →
Conditions studied
- Hemophilia — all drugs for Hemophilia →
Sponsor
Yuzuncu Yil University
Who can join
Adults 18 to 65, male only, with Hemophilia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Introduction: Hemarthrosis is the most common type of bleeding with 70-80% in patient with hemophilia (PwH) and the majority of hemarthrosis occurs in the knee and ankle joints. Recurrent hemarthrosis may cause pain, limited range of motion (ROM), atrophy, swelling, crepitus, and decreased proprioceptive sensation and ultimately causes hemophilic arthropathy. Preventing hemarthrosis and treating arthropathy symptoms in PwH may improve static and dynamic balance and walking capacity. The aim of this study was to investigate the effects of manual therapy and structured exercises on joint health, activity pain, walking capacity and static and dynamic balance. Method: Thirty-five AwH were randomly assigned to two groups using the computerised simple randomization method: the control group (CG) and the physiotherapy group (PG). The sample sizes for the CG and PG are 17 and 18, respectively. Hemophilia type and severity, treatment regime (prophylaxis or on-demand), age, height and weight were recorded. Joint health was assessed with Hemophilia Joint Health Score (HJHS) version 2.1 by a hemophilia specialist physiotherapist. Activity pain was assessed with Numeric Pain Scale (NPS). Walking capacity was evaluated 6 Minute Walking Test (6MWT). Postural balance (static and dynamic balance) were evaluated with the Pro-kin Technobody Posturographic Platform (Pro-kin 212, Technobody s.r.l, Dalmine, 21044 Bergamo, Italy). Static stability test was used for static balance assessment. Dynamic balance was evaluated with the Limits of Stability (LoS) test. The PG received 12 physiotherapy sessions twice a week for 6 weeks. The physiotherapy intervention consisted of manual therapy and a structured, progressive exercise program. The CG continued with their routine hemophilia care.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07339410
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07339410 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yuzuncu Yil University
- Last refreshed: 14 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07339410.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing