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NCT07336225

CMR-Based Prognostic Study in Patients With Cardiac Implantable Electronic Devices

Recruiting now Last updated 27 January 2026
What this trial tests

trial testing Cardiac Magnetic Resonance Imaging in Arrhythmias in 1,500 participants. Currently enrolling.

Timeline
1 January 2010
Primary endpoint
31 December 2035
31 December 2040

Quick facts

Lead sponsorChinese Academy of Medical Sciences, Fuwai Hospital
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment1,500
Start date1 January 2010
Primary completion31 December 2035
Estimated completion31 December 2040
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Chinese Academy of Medical Sciences, Fuwai Hospital

Who can join

18 and older, any sex, with Arrhythmias. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cardiac implantable electronic devices (CIEDs) are widely used to treat patients with heart failure, malignant arrhythmias, and other conditions. However, accurately identifying suitable candidates for CIED implantation remains a clinical challenge. Cardiovascular magnetic resonance imaging (CMR) provides a comprehensive assessment of cardiac structure, function, and tissue characteristics, facilitating evaluation of the myocardial substrate for arrhythmias. This study aims to evaluate the prognostic value of multiparametric CMR-derived imaging markers in CIED patients through preoperative CMR examinations. Imaging parameters of interest include structural-functional indices, myocardial strain, late gadolinium enhancement, entropy, and T1 and T2 mapping. Long-term clinical outcomes will be obtained from existing medical records and follow-up. The primary endpoint is sudden cardiac death (SCD) or SCD-equivalent events, defined as SCD, resuscitated cardiac arrest, sustained ventricular tachycardia or ventricular fibrillation, or appropriate ICD therapy. Secondary endpoints include all-cause mortality or heart failure rehospitalization. This study aims to elucidate the role of CMR in assessing CIED treatment indications and long-term risk stratification, thereby helping to optimize CIED implantation decisions.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other trials of Cardiac Magnetic Resonance Imaging

Trials testing the same drug.

Other recruiting trials for Arrhythmias

Currently open trials in the same condition.

Other Chinese Academy of Medical Sciences, Fuwai Hospital trials

Trials by the same sponsor.

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Data sources for this page

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