Last reviewed · How we verify
NCT07334288: REALM
Retrolaminar Analgesia for LuMbar Surgery
NA trial testing Ultrasound-Guided Retrolaminar Block in Postoperative Pain in 50 participants. Currently enrolling.
1 June 2027
Quick facts
| Lead sponsor | Universidad de los Andes, Chile |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 1 March 2026 |
| Primary completion | 1 June 2027 |
| Estimated completion | 1 June 2027 |
| Sites | 1 location across Chile |
Drugs / interventions tested
- Ultrasound-Guided Retrolaminar Block
- Standard Analgesia — full drug profile →
Conditions studied
- Postoperative Pain — all drugs for Postoperative Pain →
- Lumbar Surgery — all drugs for Lumbar Surgery →
- Back Pain Lower Back Chronic — all drugs for Back Pain Lower Back Chronic →
- Opioid Analgesia — all drugs for Opioid Analgesia →
Sponsor
Universidad de los Andes, Chile — full company profile →
Who can join
Adults 18 to 80, any sex, with Postoperative Pain or Lumbar Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized controlled trial evaluates the effectiveness of ultrasound-guided retrolaminar nerve block in addition to standard multimodal analgesia for postoperative pain management in patients undergoing lumbar spine surgery. Fifty patients will be randomly assigned to receive either the retrolaminar block combined with standard pain management or standard pain management alone. The primary outcome is total opioid consumption in the first 24 hours after surgery. Secondary outcomes include pain intensity at multiple time points, time to first rescue analgesia, duration of sensory block, incidence of postoperative nausea and vomiting, length of hospital stay, patient satisfaction, and chronic pain development at 3 and 6 months follow-up.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07334288
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Postoperative Pain
Currently open trials in the same condition.
- NCT07452120 — DIPB vs. SIFIB for Postoperative Analgesia After Hip Surgery · NA · recruiting
- NCT07396688 — Comparative Evaluation of the Effects of Calcium Hydroxide and BIO-C Temp Medicaments on Postoperative Pain in Patients · NA · recruiting
- NCT07413055 — Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Sur · Phase 3 · recruiting
- NCT07496086 — External Oblique Intercostal Block Versus Transversus Abdominis Plane Combined With Rectus Sheath Block on Postoperative · NA · recruiting
- NCT07396545 — External Oblique Intercostal Block Versus Erector Spinae Plane Block on Postoperative Pain in Laparoscopic Radical Gastr · NA · recruiting
Other Universidad de los Andes, Chile trials
Trials by the same sponsor.
- NCT07063914 — Stratified-Care School-Based Intervention for Adolescent Suicidal Ideation · NA · recruiting
- NCT07001202 — Acceptability and Feasibility of Reframe-IT+U for Suicidality in University Students. · NA · not yet recruiting
- NCT06630143 — The Effectiveness of Combined Virtual and Clinical Simulation in Midwifery Students · NA · completed
- NCT07034235 — Effect of Wet and Overwet Dentin on the Clinical Performance of Two Universal Adhesive Systems · NA · completed
- NCT06757842 — Acceptability and Feasibility of an In-person 8-week Mindfulness-Based Cognitive Therapy Program Among Undergraduates · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07334288 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad de los Andes, Chile
- Last refreshed: 13 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07334288.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing