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NCT07332715
Predictive Value of the Uric Acid/Albumin Ratio and Lactate in Sepsis Patients
trial testing Non-interventional / Observational Study in Sepsis-Related Mortality in 80 participants. Not yet recruiting.
15 May 2026
Quick facts
| Lead sponsor | Istinye University |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 80 |
| Start date | 15 January 2026 |
| Primary completion | 15 May 2026 |
| Estimated completion | 31 May 2026 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Non-interventional / Observational Study
Conditions studied
- Sepsis-Related Mortality — all drugs for Sepsis-Related Mortality →
- Acute Kidney Injury — all drugs for Acute Kidney Injury →
Sponsor
Istinye University
Who can join
65 and older, any sex, with Sepsis-Related Mortality or Acute Kidney Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Sepsis is a life-threatening condition characterized by organ dysfunction resulting from a dysregulated host response to infection and remains a leading cause of morbidity and mortality in intensive care units. Early identification of patients at high risk for adverse outcomes is essential for timely intervention and improved prognosis. This prospective, single-center, non-interventional study aims to evaluate the predictive value of the combined use of the blood uric acid/albumin ratio (UAR) and serum lactate levels in patients aged 65 years and older who are admitted to the intensive care unit with a diagnosis of sepsis according to SEPSIS-3 criteria. Patients without acute kidney injury at admission and with at least 24 hours of intensive care follow-up will be included. The primary outcome is the development of acute kidney injury within the first 7 days of ICU admission according to KDIGO criteria. Secondary outcomes include vasopressor requirement during ICU stay, changes in serum lactate levels over the first 24 hours, and 28-day mortality. The study seeks to determine whether the combination of UAR and lactate levels can serve as an easily accessible and clinically applicable biomarker to predict adverse outcomes and support prognostic assessment and treatment strategies in sepsis patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07332715 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istinye University
- Last refreshed: 13 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07332715.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing