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NCT07329413: TMD-POSTOP
Effect of Anterior Disc Displacement With Reduction on Postoperative Pain After Root Canal Treatment
NA trial testing Single-Visit Conventional Root Canal Treatment Using Nickel-Titanium Rotary Instruments (Endoart Smart Gold) in Symptomatic Apical Periodontitis in 70 participants. Completed in 14 July 2025.
1 July 2025
Quick facts
| Lead sponsor | Recep Tayyip Erdogan University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 70 |
| Start date | 10 March 2025 |
| Primary completion | 1 July 2025 |
| Estimated completion | 14 July 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Single-Visit Conventional Root Canal Treatment Using Nickel-Titanium Rotary Instruments (Endoart Smart Gold)
- Ibuprofen 400 mg (if necessary) — full drug profile →
Conditions studied
- Symptomatic Apical Periodontitis — all drugs for Symptomatic Apical Periodontitis →
- Temporomandibular Disorders (TMDs) — all drugs for Temporomandibular Disorders (TMDs) →
- Anterior Disc Displacement — all drugs for Anterior Disc Displacement →
Sponsor
Recep Tayyip Erdogan University
Who can join
Adults 18 to 65, any sex, with Symptomatic Apical Periodontitis or Temporomandibular Disorders (TMDs). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to evaluate the impact of anterior disc displacement with reduction (ADDR) on postoperative pain following root canal treatment in patients diagnosed with symptomatic apical periodontitis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07329413
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07329413 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Recep Tayyip Erdogan University
- Last refreshed: 9 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07329413.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing