NCT07327437 is a NA clinical trial of Grand-Knot Technique in Rotator Cuff Tear, sponsored by Sherif Hamdy Zawam.

Who is sponsoring NCT07327437?

NCT07327437 is sponsored by Sherif Hamdy Zawam.

What drugs are being tested in NCT07327437?

Interventions in NCT07327437: Grand-Knot Technique, All-Suture Anchors (Y-Knot RC).

What condition does NCT07327437 study?

NCT07327437 studies Rotator Cuff Tear.

Is NCT07327437 still recruiting?

NCT07327437 is currently completed. Last updated 8 January 2026.

Last reviewed 2026-01-08 · How we verify

NCT07327437

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Arthroscopic Trans-osseous Rotator-Cuff Repair Using the Giant-Needle and Grand-Knot Technique.

Completed NA Last updated 8 January 2026

What this trial tests

NA trial testing Grand-Knot Technique in Rotator Cuff Tear in 160 participants. Completed in 1 July 2025.

Timeline

1 January 2021

Primary endpoint
1 January 2023

1 July 2025

Quick facts

Lead sponsor	Sherif Hamdy Zawam
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	160
Start date	1 January 2021
Primary completion	1 January 2023
Estimated completion	1 July 2025
Sites	1 location across Egypt

Drugs / interventions tested

Grand-Knot Technique
All-Suture Anchors (Y-Knot RC)

Conditions studied

Rotator Cuff Tear — all drugs for Rotator Cuff Tear →

Sponsor

Sherif Hamdy Zawam

Who can join

Adults 45 to 75, any sex, with Rotator Cuff Tear. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to compare a novel, cost-effective arthroscopic trans-osseous rotator cuff repair technique, known as the 'Grand-Knot' technique, against the standard repair using all-suture anchors. The study evaluates which method provides better functional recovery and structural healing for patients with full-thickness supraspinatus tears. Patients were randomized to receive either the Grand-Knot repair or the standard anchor repair and were followed for a minimum of 2.5 years to assess shoulder function using the ASES score, range of motion, and tendon integrity."

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Rotator Cuff Tear

Currently open trials in the same condition.

NCT07412184 — Research and Clinical Validation of a Wearable Device-Based Remote Rehabilitation System for Postoperative Rotator Cuff · NA · recruiting
NCT06918041 — FiberLocker® System Augmentation of Rotator Cuff Repairs · NA · recruiting
NCT07005063 — Rotator Cuff Tendon Repair With FiberLocker System Patch Augmentation · NA · recruiting
NCT06878391 — ISB With SSNB & ANB · NA · recruiting
NCT06766630 — Exploring the Feasibility of Silk Fibroin Surgical Mesh in Rotator Cuff Tears Repair Enhancement · Phase 2, PHASE3 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07327437 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Sherif Hamdy Zawam
Last refreshed: 8 January 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07327437.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing