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NCT07326761: Microplastics
Microplastic Exposure in Neonates Receiving Parenteral Nutrition: A Prospective Cohort Study in the NICU
NA trial testing No Intervention: Observational Cohort in Microplastics Exposure in 12 participants. Completed in 1 November 2025.
1 November 2025
Quick facts
| Lead sponsor | Huiyi Li |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | screening |
| Enrollment | 12 |
| Start date | 1 January 2025 |
| Primary completion | 1 November 2025 |
| Estimated completion | 1 November 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- No Intervention: Observational Cohort — full drug profile →
Conditions studied
- Microplastics Exposure — all drugs for Microplastics Exposure →
Sponsor
Huiyi Li
Who can join
Adults 1 Hour to 2 Months, any sex, with Microplastics Exposure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to explore a potential exposure risk in the neonatal intensive care unit, namely, the iatrogenic microplastic exposure that critically ill newborns may face when receiving life-saving parenteral nutrition (intravenous nutrition delivered through a plastic infusion system). Therefore, the investigators designed a prospective study. By comparing three groups of newborns-those requiring long-term intravenous nutrition, short-term intravenous nutrition, and no intravenous nutrition-and collecting blood samples with strictly contamination-proof non-plastic instruments, the investigators used high-precision Raman spectroscopy for detection. For the first time, they attempted to systematically and quantitatively analyze the microplastic load in neonatal blood and its relationship with the duration of intravenous nutrition. The aim of this study is to provide novel scientific evidence for evaluating microplastic exposure in the neonatal medical environment, with the ultimate goal of establishing a basis for developing safer clinical practices and medical material standards in the future, thereby better protecting the long-term health of vulnerable newborns.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Microplastics in neonates: an overlooked cost of parenteral nutrition.
Xu D, Liang Z, Yang Q, Li L, et al · · 2026 · PMID 42022813 · DOI 10.3389/fpubh.2026.1767555
Verify or expand the search:
- PubMed search for NCT07326761
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Huiyi Li trials
Trials by the same sponsor.
- NCT07254507 — Lung Ultrasound-Guided Positioning Strategy for the Prevention of Ventilator-Associated Pneumonia in Neonates · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07326761 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Huiyi Li
- Last refreshed: 8 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07326761.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing