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NCT07326410
Prevalence of Cerebral Large Vessel Occlusion Among Acute Ischemic Stroke Patients in Assiut University Hospitals
trial in Ischemic Stroke in 300 participants. Not yet recruiting.
1 February 2027
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 300 |
| Start date | 1 February 2026 |
| Primary completion | 1 February 2027 |
| Estimated completion | 1 March 2027 |
Conditions studied
- Ischemic Stroke — all drugs for Ischemic Stroke →
Sponsor
Assiut University
Who can join
18 and older, any sex, with Ischemic Stroke. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Prevalence of Large Vessel Occlusion among acute ischemic stroke patients in Assiut University hospitals 1. Study Objectives Primary Objective: \- To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals Secondary Objectives: * To describe clinical and radiological characteristics of LVO patients. * To assess factors associated with LVO (age, sex, stroke severity, comorbidities). 2. Study Design * Type: single center, prospective observational cross-sectional study * Duration: 12-month recruitment period * Setting: Assiut university hospitals, stroke unit. 3. Study Population Inclusion Criteria: * Adults (≥18 years) * Diagnosed with acute ischemic stroke within 24 hours of symptom onset * Underwent vascular imaging (CTA or MRA) on admission Exclusion Criteria: * Hemorrhagic stroke * Stroke mimics * Incomplete imaging data 4. Definitions Large Vessel Occlusion (LVO) defined as occlusion in: * Intracranial ICA * M1 or proximal M2 segments of MCA * Basilar artery ± Optional: A1 6. Data Collection Clinical Data: * Demographics (age, sex) * Risk factors (HTN, DM, AF, CAD, smoking) * NIHSS on admission and discharge mRS on admission and discharge * Onset-to-door time * Imaging modality used Imaging Data: * Site of occlusion * ASPECTS (optional) * Collateral status (optional if available) Hospital Data: * Facility type (public vs private) * Door-to-CT and door-to-CTA times 8. Analysis Plan * Primary: Prevalence of LVO = Number of LVO cases / Total AIS patients with vascular imaging * Subgroup analysis: By age group, sex, region, NIHSS * Secondary: Logistic regression to identify predictors of LVO
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07326410
- Europe PMC full search
- ASCO Meeting Library
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07326410 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 8 January 2026
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