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NCT07325773
Effects of Magnesium Sulfate on Oxygenation and Lung Mechanics During One-Lung Ventilation
trial in Intraoperative Oxygenation and Pulmonary Mechanics in 104 participants. Currently enrolling.
15 July 2026
Quick facts
| Lead sponsor | Marmara University |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 104 |
| Start date | 1 December 2025 |
| Primary completion | 15 July 2026 |
| Estimated completion | 28 November 2026 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Intraoperative Oxygenation and Pulmonary Mechanics — all drugs for Intraoperative Oxygenation and Pulmonary Mechanics →
Sponsor
Marmara University
Who can join
Adults 18 to 80, any sex, with Intraoperative Oxygenation and Pulmonary Mechanics. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This prospective observational study aims to evaluate the effects of intravenous magnesium sulfate on intraoperative oxygenation and lung mechanics in patients undergoing thoracic surgery with one-lung ventilation. Magnesium sulfate has been reported to have potential bronchodilatory and anti-inflammatory properties, which may improve gas exchange and respiratory mechanics during lung isolation. In this study, patients who receive magnesium sulfate as part of standard anesthetic management will be compared with those who do not receive the drug. Oxygenation parameters, dynamic and static lung mechanics, airway pressures, and ventilation-related indices will be recorded throughout the intraoperative period. The findings of this study may help clarify whether magnesium sulfate provides measurable respiratory benefits during one-lung ventilation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07325773 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Marmara University
- Last refreshed: 8 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07325773.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing