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NCT07325604
Effect of Neuromuscular Electrical Stimulation on Unilateral Central Facial Palsy
NA trial testing Neuromuscular electrical stimulation (NMES) in Facial Palsy in 130 participants. Currently enrolling.
15 December 2030
Quick facts
| Lead sponsor | University of Aarhus |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 130 |
| Start date | 27 February 2026 |
| Primary completion | 15 December 2030 |
| Estimated completion | 15 December 2030 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Neuromuscular electrical stimulation (NMES)
- Usual Care
Conditions studied
- Facial Palsy — all drugs for Facial Palsy →
- Stroke — all drugs for Stroke →
Sponsor
University of Aarhus
Who can join
18 and older, any sex, with Facial Palsy or Stroke. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background Central facial palsy (CFP) is a common condition in stroke, with an estimated prevalence of 45%. CFP can lead to facial asymmetry, problems with mouth closure and food processing, bite marks on the cheek, social isolation, and reduced quality of life. CFP is seen as an important area of rehabilitation, and training is therefore often carried out to reduce the consequences of CFP. In a recent systematic review conducted by the principal investigator, the results showed that very few studies have been conducted that have investigated the effect of training for CFP, and there is currently no scientific evidence to support the effect of the various training interventions. Objective To investigate the effect of Neuromuscular electrical stimulation (NMES) on facial symmetry compared to usual practice, in participants with CFP as a result of stroke. Hypothesis: Participants who receive training with NMES together with usual training for facial paralysis have greater improvement in facial symmetry than participants who only receive usual training for facial paralysis. Trial design Randomized controlled trial (RCT) with a nested pilot trial. A pilot trial/RCT will be conducted in order to power calculation in an RCT. The protocol for the pilot trial and RCT will be the same, and participants from the pilot trial and their outcome data are thus expected to be included in the RCT.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07325604
- Europe PMC full search
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Related trials
Other trials of Neuromuscular electrical stimulation (NMES)
Trials testing the same drug.
- NCT07075497 — Effects of Combining PNF With NMES in Young Football Players · NA · completed
- NCT06648356 — Effects of Combining PNF With NMES in Young Basketball Players · NA · completed
- NCT05536531 — NMES Role to Prevent Respiratory Muscle Weakness in Critically Ill Patients and Its Association to Changes in Myokines. · NA · recruiting
- NCT06478914 — Neuromuscular Electrical Stimulation Versus Low-intensity Laser on Motor Conduction Velocity of the Common Peroneal Nerv · NA · completed
- NCT04969094 — Reducing Fall Risk With NMES · NA · active not recruiting
Other recruiting trials for Facial Palsy
Currently open trials in the same condition.
- NCT06532903 — Functional Recovery From Facial Paralysis · NA · recruiting
- NCT06579235 — Explorative Proteomics in Pediatric Neuroborreliosis · active not recruiting
- NCT03781700 — Evaluation of Cortisone Treatment in Children With Acute Facial Nerve Palsy · Phase 4 · recruiting
Other University of Aarhus trials
Trials by the same sponsor.
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- NCT07451028 — Effect of an Oral Neuromuscular Training Device on Dysphagia · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07325604 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Aarhus
- Last refreshed: 9 March 2026
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