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NCT07325149
The Effect of Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation on Bone Strength.
NA trial testing Exoskeleton-Assisted Walking (EAW) + active Transcutaneous Spinal Cord Stimulation (tSCS) in Secondary Osteoporosis in 24 participants. Not yet recruiting.
30 June 2031
Quick facts
| Lead sponsor | Bronx VA Medical Center |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 24 |
| Start date | 1 July 2026 |
| Primary completion | 30 June 2031 |
| Estimated completion | 1 June 2033 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Exoskeleton-Assisted Walking (EAW) + active Transcutaneous Spinal Cord Stimulation (tSCS)
- Exoskeleton-assisted walking (EAW) + sham Transcutaneous Spinal Cord Stimulation (tSCS)
Conditions studied
- Secondary Osteoporosis — all drugs for Secondary Osteoporosis →
- Sarcopenia — all drugs for Sarcopenia →
Sponsor
Bronx VA Medical Center
Who can join
Adults 21 to 60, any sex, with Secondary Osteoporosis or Sarcopenia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Immobilization following spinal cord injury (SCI) results in muscle and bone loss below the level of injury, which ultimately predisposes to fracture at several sites throughout the legs and can lead to several medical complications that can devastate quality of life. There is a scarcity of research that has successfully implemented rehabilitation and/or exercise training interventions to preserve the musculoskeletal system during the acute phase SCI, or possibly reverse the muscle and bone loss that has already occurred in chronic SCI. This study will compare the effect of exoskeleton-assisted walking (EAW) training combined with transcutaneous spinal cord stimulation (tSCS) (EAW + active tSCS), to that of EAW + sham tSCS, on measures of muscle and bone health in a cohort of chronically injured motor incomplete SCI. A successful outcome would expand treatment options to improve musculoskeletal health over the lifetime.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07325149
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Related trials
Other Bronx VA Medical Center trials
Trials by the same sponsor.
- NCT06104735 — Finding the Best Combination of Brain and Spinal Cord Stimulation With Hand Training After Spinal Cord Injury · NA · recruiting
- NCT05708274 — Pharmacological Agents for Chronic Spinal Cord Injury (SCI) · Phase 1 · completed
- NCT04727866 — Brain Plus Spinal Stimulation for Cervical SCI · NA · completed
- NCT03851302 — Effects of Remote Ischemic Conditioning on Hand Use in Individuals With SCI and ALS · NA · completed
- NCT03806023 — EMG Triggered Closed-Loop Stimulation for Spinal Cord Injury Individuals · NA · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07325149 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Bronx VA Medical Center
- Last refreshed: 8 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07325149.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing