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NCT07324070: RMTSECT2
Electroconvulsive Therapy Augmented With Transcranial Magnetic Stimulation for Treatment Resistant Depression
NA trial testing Electroconvulsive therapy in Major Depressive Disorder (MDD) in 50 participants. Currently enrolling.
5 January 2028
Quick facts
| Lead sponsor | Charles University, Czech Republic |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | factorial |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 5 January 2026 |
| Primary completion | 5 January 2028 |
| Estimated completion | 5 January 2029 |
| Sites | 1 location across Czechia |
Drugs / interventions tested
- Electroconvulsive therapy
- Transcranial Magnetic Stimulation — full drug profile →
Conditions studied
- Major Depressive Disorder (MDD) — all drugs for Major Depressive Disorder (MDD) →
- Treatment Resistant Depression (TRD) — all drugs for Treatment Resistant Depression (TRD) →
Sponsor
Charles University, Czech Republic
Who can join
18 and older, any sex, with Major Depressive Disorder (MDD) or Treatment Resistant Depression (TRD). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The RTMSECT2 study was design to compare the application of electroconvulsive therapy augmented by transcranial magnetic stimulation. Subject will be compared both within groups and in group using psychometric scales and different deliver energy
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07324070
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT05465915 — Pulse Width 0.15ms vs 0.30ms in Electroconvulsive Therapy · EARLY_PHASE1 · unknown
- NCT05135897 — The Neurobiological Fundaments of Depression and Its Relief Through Neurostimulation Treatments · unknown
Other recruiting trials for Major Depressive Disorder (MDD)
Currently open trials in the same condition.
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- NCT07226661 — Double-blind, Placebo-controlled Study in Adults With Major Depressive Disorder · Phase 2 · recruiting
- NCT06972368 — Home-Based tDCS for Depression in BPD · NA · recruiting
- NCT07294924 — Prediction of REsponse to Depression Interventions (Accelerated rTMS) Using Clinical and TD-fNIRS Measurements · recruiting
- NCT06773949 — Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat Depression · NA · recruiting
Other Charles University, Czech Republic trials
Trials by the same sponsor.
- NCT07475481 — Exercise-Based Strategies for Chronic Back Pain · NA · not yet recruiting
- NCT07468318 — Multimodal Therapy for Somatosensory Tinnitus · NA · not yet recruiting
- NCT07525154 — Development of a Certified Testing Procedure for Hip and Groin Injuries in Athletes · NA · not yet recruiting
- NCT07512570 — Feasibility and Preliminary Effects of a Structured Resistance Training Program in Children Aged 10-14 Years · NA · not yet recruiting
- NCT07424326 — Extended Ablation Versus Pulmonary Vein Isolation to Treat Persistent Atrial Fibrillation · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07324070 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Charles University, Czech Republic
- Last refreshed: 7 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07324070.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing