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Efficacy of Combining Ultrasound-Guided Needle Release of Transverse Carpal Ligament and Median Nerve Dextrose Water Hydrodissection for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is a common musculoskeletal disorder, which is caused by compression of the median nerve as it travels through the wrist. There are several treatments for CTS, including conservative and surgical options. Though local corticosteroid injection has been considered more effective than physical therapy for treatment of CTS and has significant short-term benefits, long term benefits are not evidenced. Several studies in recent years reported significantly superior longer-term benefit of D5W and PRP compared with corticosteroid injections and other conservative managements. In addition, percutaneous release of the transverse carpal ligament (TCL) was developed to treat CTS in recent years. Because the effectiveness of the recently developed techniques in treating CTS has not been well established, the investigators aim to investigate whether combining US-guided partial release of the transverse carpal ligament with a needle plus D5W hydrodissection is more beneficial for CTS comparing to either treatment alone.
Details
| Lead sponsor | Shin Kong Wu Ho-Su Memorial Hospital |
|---|---|
| Phase | NA |
| Status | NOT_YET_RECRUITING |
| Enrolment | 102 |
| Start date | Thu Jan 01 2026 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Tue Dec 31 2030 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Carpal Tunnel Syndrome
- Dextrose
- Carpal Tunnel Release
- Ultrasound
- Nerve Hydrodissection Therapy
Interventions
- Active Comparator: US-guided D5W perineural hydrodissection alone, group A
- Active Comparator: US guided partial release of the TCL with a needle + D5W injection (to TCL), group B
- Active Comparator: US-guided partial release of the TCL with D5W injection to TCL plus D5W perineural hydrodissection, group C
Countries
Taiwan