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NCT07320417

Schneider Membrane Preservation With In Situ Osteogenesis: A Modified Maxillary Resection Study

Recruiting now NA Last updated 27 January 2026
What this trial tests

NA trial testing chneiderian Membrane-Preserving in Maxillary Diseases in 18 participants. Currently enrolling.

Timeline
1 May 2025
Primary endpoint
8 June 2026
10 June 2026

Quick facts

Lead sponsorWenzhao Guan
PhaseNA
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment18
Start date1 May 2025
Primary completion8 June 2026
Estimated completion10 June 2026
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Wenzhao Guan

Who can join

Adults 18 to 75, any sex, with Maxillary Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This case series study aimed to find out if a new surgical technique that preserves the sinus membrane during upper jaw removal can help patients regenerate bone and recover function better after surgery. The study included two female patients with jaw tumors who were not suitable for or did not want complex reconstruction with tissue flaps. The main questions the study tried to answer were: Can the preserved sinus membrane help new bone grow spontaneously in the jaw defect area after surgery? Can this new method reduce common complications seen with traditional surgery, such as oronasal fistula and empty nose syndrome? How well can patients recover in terms of chewing, swallowing, speech, and quality of life after the procedure? In the study, during surgery, the surgeon carefully separated and preserved the sinus membrane from the bone that needed to be removed. After surgery, patients were followed with regular CT scans to check new bone growth. They also underwent tests to measure chewing force, swallowing ability, speech function, and quality of life to evaluate the long-term outcomes of this technique.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Data sources for this page

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