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NCT07319338
Objective Vascular Biomarkers as Triage for Depression in Chronic Atrophic Gastritis
trial testing Vascular-Psychological Triage Workflow in Chronic Atrophic Gastritis in 520 participants. Not yet recruiting.
20 June 2026
Quick facts
| Lead sponsor | China Academy of Chinese Medical Sciences |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 520 |
| Start date | 1 February 2026 |
| Primary completion | 20 June 2026 |
| Estimated completion | 30 August 2026 |
| Sites | 4 locations across China |
Drugs / interventions tested
- Vascular-Psychological Triage Workflow
Conditions studied
- Chronic Atrophic Gastritis — all drugs for Chronic Atrophic Gastritis →
- Depressive Symptoms — all drugs for Depressive Symptoms →
- Depression — all drugs for Depression →
- Gastrointestinal Diseases — all drugs for Gastrointestinal Diseases →
Sponsor
China Academy of Chinese Medical Sciences — full company profile →
Who can join
Adults 20 to 60, any sex, with Chronic Atrophic Gastritis or Depressive Symptoms. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Depressive symptoms are highly prevalent in patients with chronic atrophic gastritis (CAG) but are frequently under-detected due to stigma and reliance on subjective questionnaires. This multicenter, cross-sectional observational study aims to validate a novel clinical triage workflow. It repurposes routine vascular assessments (specifically dorsalis pedis artery ultrasound and arterial stiffness metrics) as objective "biological entry points" to facilitate mental health referrals. The study will enroll approximately 450-520 adults with histologically confirmed CAG across four clinical centers in China. The primary objective is to determine the diagnostic accuracy of these vascular biomarkers for identifying patients with moderate-to-severe depressive symptoms (PHQ-9 score \>= 10). Secondary objectives include evaluating the implementation feasibility (e.g., referral uptake, screening completion rate) of this integrated care model in routine gastroenterology practice.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Vascular and autonomic correlates of screening-positive depressive symptom burden in chronic atrophic gastritis: a multicenter observational study protocol.
Wang M, Jiang S, Jin Z, Pan X, et al · · 2026 · PMID 42164162 · DOI 10.3389/fmed.2026.1842882
Verify or expand the search:
- PubMed search for NCT07319338
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Chronic Atrophic Gastritis
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07319338 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by China Academy of Chinese Medical Sciences
- Last refreshed: 6 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07319338.
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