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NCT07319104: FECCO-BioBank
Liquid Biopsy in Early Colorectal Lesions
trial testing Venous blood sampling in Colorectal Neoplasms in 1,000 participants. Not yet recruiting.
1 December 2028
Quick facts
| Lead sponsor | University Hospital, Montpellier |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 1,000 |
| Start date | 1 March 2026 |
| Primary completion | 1 December 2028 |
| Estimated completion | 1 September 2031 |
| Sites | 12 locations across France |
Drugs / interventions tested
- Venous blood sampling
Conditions studied
- Colorectal Neoplasms — all drugs for Colorectal Neoplasms →
- Precancerous Conditions — all drugs for Precancerous Conditions →
- Adenocarcinoma of the Colon — all drugs for Adenocarcinoma of the Colon →
- Lymphatic Metastasis — all drugs for Lymphatic Metastasis →
Sponsor
University Hospital, Montpellier
Who can join
18 and older, any sex, with Colorectal Neoplasms or Precancerous Conditions. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Early colorectal cancer screening increasingly detects small superficial colonic lesions, but current diagnostic tools still struggle to distinguish benign from malignant lesions and to assess lymph node risk. As histology after resection has limited accuracy, many patients undergo unnecessary surgery. Liquid biopsy, analyzing circulating biomarkers such as tumor DNA, extracellular vesicles, and nucleosomes, offers a non-invasive way to better classify these lesions. Emerging evidence suggests it may outperform current criteria for predicting lymph node involvement in T1 colorectal cancer. This study will establish a biobank of 1,000 patients to identify blood-based signatures that predict tumor stage and lymph node status. The hypothesis of the study is that circulating biomarkers can accurately differentiate benign from malignant lesions and identify patients with or without lymph node metastasis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07319104
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07319104 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Montpellier
- Last refreshed: 22 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07319104.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing