NCT07313215 is a NA clinical trial of Rifampicin (R) in Periprosthetic Joint Infection, sponsored by First Affiliated Hospital of Fujian Medical University.

Who is sponsoring NCT07313215?

NCT07313215 is sponsored by First Affiliated Hospital of Fujian Medical University.

What drugs are being tested in NCT07313215?

Interventions in NCT07313215: Rifampicin (R).

What condition does NCT07313215 study?

NCT07313215 studies Periprosthetic Joint Infection.

Is NCT07313215 still recruiting?

NCT07313215 is currently recruiting now. Last updated 31 December 2025.

Last reviewed 2025-12-31 · How we verify

NCT07313215

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Rifampin-combined Antibiotic Therapy for Staphylococcal PJI

Recruiting now NA Last updated 31 December 2025

What this trial tests

NA trial testing Rifampicin (R) in Periprosthetic Joint Infection in 428 participants. Currently enrolling.

Timeline

13 November 2025

Primary endpoint
30 June 2027

18 December 2027

Quick facts

Lead sponsor	First Affiliated Hospital of Fujian Medical University
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	428
Start date	13 November 2025
Primary completion	30 June 2027
Estimated completion	18 December 2027
Sites	1 location across China

Drugs / interventions tested

Rifampicin (R) — full drug profile →

Conditions studied

Periprosthetic Joint Infection — all drugs for Periprosthetic Joint Infection →

Sponsor

First Affiliated Hospital of Fujian Medical University

Who can join

Adults 18 to 80, any sex, with Periprosthetic Joint Infection. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a prospective, multicenter, randomized controlled study. Patients were evaluated through inclusion and exclusion criteria. Patients who meet the conditions will sign an informed consent form. After DAIR surgery, they will be treated with intravenous antibiotics for 1-2 weeks and then randomly assigned to one of the following two groups: Antibiotic treatment group: All enrolled patients will be treated with antibiotics (fluoroquinolones or linezolid) for 3 months based on the results of microbial culture and drug sensitivity after surgery. Rifampicin combined with antibiotics treatment group: In addition to the above-mentioned antibiotics, all enrolled patients were treated with rifampicin for 3 months after the operation. The infection control rates of the two groups were judged through at least 2-year follow-up after the operation.The study will follow the Consolidated Standards of Reporting Trials (CONSORT) guidelines for reporting parallel group randomised trials. Ethical approval will be obtained from each institution. Written informed consent will be obtained from all participants to ensure their voluntary participation and understanding of the study.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Rifampicin (R)

Trials testing the same drug.

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NCT07076225 — Ultra-Short Regimen for Elderly DS-TB · Phase 3 · not yet recruiting
NCT07213765 — Short-term Antibiotic Therapy in Mycobacterium Avium Complex Pulmonary Disease · Phase 4 · recruiting
NCT06114628 — Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB · Phase 2 · recruiting

Other recruiting trials for Periprosthetic Joint Infection

Currently open trials in the same condition.

NCT06464770 — Optimizing Infection Prophylaxis Prior to Shoulder Surgery · NA · recruiting
NCT06268795 — A Diagnostic Test Accuracy Study Comparing Biopsy to Aspiration in Shoulder and Elbow Arthroplasty Revision Surgery (BAS · recruiting
NCT05284318 — Prospective Cohort Study on Antibiotic Course and Efficacy After Two-stage Revision in PJI. · recruiting

Other First Affiliated Hospital of Fujian Medical University trials

Trials by the same sponsor.

NCT07513844 — Optimizing Parameters of Low-Intensity Focused Ultrasound for Pallidal Modulation in Huntington's Disease · NA · not yet recruiting
NCT07337772 — Comparing Different Doses of Corticosteroids in Local Infiltration Analgesia (LIA) for Total Knee Arthroplasty · NA · recruiting
NCT07369401 — Deep Brain Stimulation of the Nucleus Accumbens and Anterior Limb of the Internal Capsule in the Treatment of Refractory · NA · not yet recruiting
NCT07378358 — Evaluation of AI Large Models for Diagnosis and Treatment in Real-World Cases: Multicenter Retrospective Study · recruiting
NCT07363382 — The Value of GRPR PET Imaging for Diagnosis and Staging in Prostate Cancer · Phase 1, PHASE2 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07313215 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by First Affiliated Hospital of Fujian Medical University
Last refreshed: 31 December 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07313215.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing