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NCT07311447: TCI-NEURO

Target-Controlled Infusion and Postoperative Neurocognitive Outcomes in Geriatric Patients

Completed Last updated 31 December 2025
What this trial tests

trial in Postoperative Cognitive Dysfunction (POCD) in 50 participants. Completed in 31 October 2025.

Timeline
5 May 2025
Primary endpoint
31 October 2025
31 October 2025

Quick facts

Lead sponsorNamigar Turgut
StatusCompleted
Study typeOBSERVATIONAL
Enrollment50
Start date5 May 2025
Primary completion31 October 2025
Estimated completion31 October 2025
Sites1 location across Turkey (Türkiye)

Conditions studied

Sponsor

Namigar Turgut

Who can join

65 and older, any sex, with Postoperative Cognitive Dysfunction (POCD) or Neurocognitive Function. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This prospective observational study aims to evaluate the effects of target-controlled infusion (TCI) on postoperative neurocognitive function in geriatric patients undergoing major non-cardiac surgery. Elderly patients are at increased risk of postoperative cognitive dysfunction due to physiological changes and anesthesia-related factors. In this study, sedation management with TCI will be compared to manual infusion. Neurocognitive function will be assessed at multiple time points using the Mini-Mental State Examination (MMSE), and sedation levels will be monitored with the Bispectral Index (BIS) and the Richmond Agitation-Sedation Scale (RASS). The study aims to provide insights into safer sedation practices and improved cognitive outcomes in elderly surgical patients.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other Namigar Turgut trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07311447.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing