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NCT07311109
A Prospective, Single-center, Randomized Controlled Clinical Study Evaluating the Efficacy and Safety of Hyperbaric Oxygen Therapy as an Adjunctive Treatment for Chronic Heart Failure
NA trial testing hyperbaric oxygen therapy in Chronic Heart Failure With Reduced Ejection Fraction in 150 participants. Not yet recruiting.
31 December 2027
Quick facts
| Lead sponsor | Fujian Medical University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 150 |
| Start date | 15 December 2025 |
| Primary completion | 31 December 2027 |
| Estimated completion | 31 December 2028 |
| Sites | 1 location across China |
Drugs / interventions tested
- hyperbaric oxygen therapy — full drug profile →
Conditions studied
- Chronic Heart Failure With Reduced Ejection Fraction — all drugs for Chronic Heart Failure With Reduced Ejection Fraction →
Sponsor
Fujian Medical University
Who can join
Adults 18 to 70, any sex, with Chronic Heart Failure With Reduced Ejection Fraction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to investigate whether adjunctive hyperbaric oxygen therapy, compared to guideline-directed medical therapy with the "New Four Pillars" (ARNI/ACEI/ARB + β-blocker + MRA + SGLT2 inhibitor) alone, improves cardiac function in patients with chronic heart failure, and to evaluate its efficacy and safety.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07311109
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT03412045 — Hyperbaric Oxygen Therapy in Sickle Cell Pain · NA · completed
Other recruiting trials for Chronic Heart Failure With Reduced Ejection Fraction
Currently open trials in the same condition.
- NCT06632483 — An Observational Study to Learn More About How Safe Vericiguat is and How Well it Works in Indian People With Chronic He · active not recruiting
- NCT06148935 — An Observational Study to Learn More About the Use of Vericiguat in Korean People With Chronic Heart Failure With Reduce · recruiting
- NCT05553886 — S086 Tablets for Chronic Heart Failure With Reduced Ejection Fraction · Phase 3 · recruiting
Other Fujian Medical University trials
Trials by the same sponsor.
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- NCT07383909 — Remote Ischemic Preconditioning for Aute Type A Aortic Dissection Surgery · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07311109 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fujian Medical University
- Last refreshed: 30 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07311109.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing