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NCT07308522
Clinical ,Microbiological and Compliance Outcomes of AI-based Toothbrushes in Plaque Induced Gingivitis
NA trial testing AI toothbrush in Plaque Induced Gingivitis in 33 participants. Not yet recruiting.
1 April 2026
Quick facts
| Lead sponsor | University of Baghdad |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 33 |
| Start date | 1 January 2026 |
| Primary completion | 1 April 2026 |
| Estimated completion | 30 June 2026 |
| Sites | 1 location across Iraq |
Drugs / interventions tested
- AI toothbrush
- Manual toothbrush
- Electric toothbrush
Conditions studied
- Plaque Induced Gingivitis — all drugs for Plaque Induced Gingivitis →
- Toothbrushing — all drugs for Toothbrushing →
- Compliance — all drugs for Compliance →
Sponsor
University of Baghdad
Who can join
Adults 18 to 35, any sex, with Plaque Induced Gingivitis or Toothbrushing. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Severe periodontitis is widespread and begins with reversible gingivitis, driven by poor oral hygiene and a dysbiotic microbiome. Daily toothbrushing is the simplest prevention, but patients still leave plaque. Electric brushes remove more plaque and reduce gingivitis better than manual ones, and users show better periodontal status. App-connected smart brushes and apps aim to improve adherence. Trials increased plaque reduction and brushing time versus manual brushing, but app layers have not clearly beaten standard power brushes, and microbiological outcomes are rarely reported. Xiaomi's AI-based sonic T501 adds pressure sensing, personalised coaching and coverage tracking, whereas the T302 is a simpler non-connected sonic brush. Streptococcus sanguinis is a health-associated early coloniser; its qPCR-measured relative abundance marks a healthy supragingival profile. It is still unclear whether AI guidance adds extra benefit beyond a standard electric brush in adult gingivitis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07308522
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Related trials
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Other University of Baghdad trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07308522 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Baghdad
- Last refreshed: 29 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07308522.
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