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NCT07302165
PreParent: Internet-based Digital Tools to Screen for and Prevent Postpartum Depression in Parents-to-be
NA trial testing Online prenatal affective cognitive training in Post-partum Depression in 520 participants. Enrolling by invitation.
28 February 2027
Quick facts
| Lead sponsor | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 520 |
| Start date | 30 August 2025 |
| Primary completion | 28 February 2027 |
| Estimated completion | 28 February 2027 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Online prenatal affective cognitive training
Conditions studied
- Post-partum Depression — all drugs for Post-partum Depression →
Sponsor
Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Who can join
18 and older, any sex, with Post-partum Depression. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this randomized controlled study is to evaluate whether an online intervention that combines psychoeducation and affective cognitive training can help prevent postpartum depression in pregnant women and co-parents who have been identified as having risk factors for postpartum depression through an online screening tool. A total of 520 expecting parents will be enrolled in the intervention trial. Researchers will compare the online intervention to care as usual (CAU) in the Danish healthcare system to determine whether the intervention has a better preventive effect. The study also involves a low-risk comparison group (n = 5250) who will not receive the intervention but will complete the same assessments for background comparisons. The main question is: \- Does the online intervention reduce the number of mothers who develop postpartum depression during the first six months after birth? Other questions the study addresses include: * How severe mothers' depressive symptoms are during the first six weeks postpartum, based on weekly online ratings? * How do parents report their own stress levels and their infant's development six months after birth? The study will also explore: * How many co-parents develop postpartum depression during the first six months postpartum. * Whether mothers experience additional benefit if their co-parent also completes the intervention. Participants will: * Complete a 4-5-week online intervention with 8-9 modules that include psychoeducation and cognitive-affective training. * Complete online questionnaires and outcome assessments from home. * Participate in a diagnostic interview by phone after birth.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07302165
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Other Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07302165 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
- Last refreshed: 24 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07302165.
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