Morning Versus Evening Patching in Childhood Amblyopia

NCT07294599 NA NOT_YET_RECRUITING

To determine whether the time of day at which daily occlusion (patching) is administered - morning (08:00-10:00) versus evening (17:00-19:00) - affects the amount of visual-acuity improvement in the amblyopic eye in children with unilateral amblyopia. Rationale: While occlusion therapy remains the mainstay for treatment of childhood amblyopia, existing trials have focused on patching duration, not on the timing of occlusion. Diurnal or chronobiological factors - such as fluctuations in neuroplasticity, attention, compliance, or visual demand during the day - may influence the efficacy of patching. Understanding whether timing matters could help optimize occlusion therapy, improve outcomes, and reduce treatment burden.

Details

Lead sponsor	Yarmouk University
Phase	NA
Status	NOT_YET_RECRUITING
Enrolment	100
Start date	Sun Dec 14 2025 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Sun Jun 14 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Amblyopia

Interventions

• eye-patching