Last reviewed · How we verify
NCT07292623: tVNS_older
Effects of Transcutaneous Vagus Nerve Stimulation in Older Adults
NA trial testing Active location tVNS in Older Adults Without Any Specific Clinical Condition in 12 participants. Completed in 12 February 2026.
10 February 2026
Quick facts
| Lead sponsor | Universidade da Coruña |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 12 |
| Start date | 19 December 2025 |
| Primary completion | 10 February 2026 |
| Estimated completion | 12 February 2026 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Active location tVNS
- Sham Comparator
Conditions studied
- Older Adults Without Any Specific Clinical Condition — all drugs for Older Adults Without Any Specific Clinical Condition →
- Autonomic Nervous System Imbalance — all drugs for Autonomic Nervous System Imbalance →
- Transcutaneous Vagus Nerve Stimulation — all drugs for Transcutaneous Vagus Nerve Stimulation →
Sponsor
Universidade da Coruña
Who can join
Adults 65 to 80, any sex, with Older Adults Without Any Specific Clinical Condition or Autonomic Nervous System Imbalance. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The autonomic nervous system consists of two branches, the sympathetic and the parasympathetic, which must work in balance. Its functioning can be measured indirectly by heart rate variability, which is the time between heartbeats, which is not constant. The more it varies, the greater the role of the parasympathetic branch, and vice versa. However, with age, an imbalance can occur and the parasympathetic branch can play a lesser role, resulting in less heart rate variability (the times between heartbeats become more similar). The aim of this study is to know if electrical stimulation in the ear can improve the balance between the two branches of the autonomic nervous system in older adults, comparing two different locations of application. The main questions to answer are: Does applying electrical stimulation to a specific area of the ear improve the balance of the autonomic nervous system? Does it also help improve hand tremors, balance, concentration, saliva production, and voice quality?
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07292623
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07292623 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidade da Coruña
- Last refreshed: 2 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07292623.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing