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NCT07292103
Trauma Exposure and Childhood Trauma in Temporomandibular Joint Disorders
trial in Temporomandibular Disorder in 102 participants. Completed in 10 October 2025.
10 October 2025
Quick facts
| Lead sponsor | Gulseren Demir Karakilic |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 102 |
| Start date | 22 May 2025 |
| Primary completion | 10 October 2025 |
| Estimated completion | 10 October 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Temporomandibular Disorder — all drugs for Temporomandibular Disorder →
- Temporomandibular Joint Dysfunction — all drugs for Temporomandibular Joint Dysfunction →
- Trauma Exposure — all drugs for Trauma Exposure →
- Childhood Traumas — all drugs for Childhood Traumas →
Sponsor
Gulseren Demir Karakilic
Who can join
Adults 18 to 65, any sex, with Temporomandibular Disorder or Temporomandibular Joint Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Temporomandibular disorder is a multifactorial condition that involves the temporomandibular joint, masticatory muscles, and surrounding structures and is influenced by biological, psychological, and social factors. Parafunctional habits, bruxism, trauma, and occlusal discrepancies have been recognized as important etiological contributors, while psychosocial stressors and early life experiences also play a critical role. Adverse childhood experiences, including neglect and abuse, have been identified as risk factors for long-term psychological vulnerability and physical health problems. Trauma exposure throughout life may further increase the risk of temporomandibular symptoms and negatively affect functional outcomes and quality of life. The present prospective, cross-sectional case-control study aims to investigate the frequency and impact of childhood trauma and lifetime trauma exposure on functional outcomes and health-related quality of life in patients with temporomandibular disorder. A clinical sample of patients diagnosed with temporomandibular disorder is compared with healthy individuals matched for age and sex. All participants complete standardized questionnaires assessing mandibular function, symptoms of anxiety and depression, cumulative trauma exposure across childhood, adolescence, and adulthood, childhood maltreatment, and health-related quality of life. By systematically integrating validated measures of both early and later traumatic experiences, this study seeks to provide a comprehensive understanding of the contribution of trauma to the severity and psychosocial burden of temporomandibular disorder. The findings are expected to emphasize the importance of incorporating trauma screening and psychological assessment into the routine evaluation and multidisciplinary management of patients with temporomandibular disorder.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07292103
- Europe PMC full search
- ASCO Meeting Library
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Related trials
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Currently open trials in the same condition.
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- NCT06365151 — An Algorithm for Approaching Temporomandibular Disorders With Osteopathic Manual Therapy in Patients With Fibromyalgia · NA · recruiting
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Other Gulseren Demir Karakilic trials
Trials by the same sponsor.
- NCT07292181 — Central Sensitization and Neuropathic Pain in Cervicogenic Headache · completed
- NCT07292155 — Type D Personality, and Stigma in Myofascial Pain Syndrome · completed
- NCT07292129 — Smartphone Addiction in Cervicogenic Headache · completed
- NCT07292077 — Restless Legs Syndrome in Temporomandibular Joint Disorders · completed
- NCT07292064 — Type D Personality, Somatization and Perceived Social Support in Temporomandibular Joint Disorders · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07292103 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Gulseren Demir Karakilic
- Last refreshed: 29 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07292103.
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