NCT07289919 is a NA clinical trial of Echium oil in Cardiovascular (CV) Risk, sponsored by University of Sao Paulo.

Who is sponsoring NCT07289919?

NCT07289919 is sponsored by University of Sao Paulo.

What drugs are being tested in NCT07289919?

Interventions in NCT07289919: Echium oil, Ahiflower oil, EPA capsules.

What condition does NCT07289919 study?

NCT07289919 studies Cardiovascular (CV) Risk, Atheroscleroses, Inflamation, Omega 3 Fatty Acids, Supplement.

Is NCT07289919 still recruiting?

NCT07289919 is currently active, enrolled. Last updated 17 December 2025.

Last reviewed 2025-12-17 · How we verify

NCT07289919

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Exploring Sustainable Alternatives to Marine Oils With Echium and Ahiflower Oils

Active, enrolled NA Last updated 17 December 2025

What this trial tests

NA trial testing Echium oil in Cardiovascular (CV) Risk in 15 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

26 May 2025

Primary endpoint
5 March 2026

31 December 2026

Quick facts

Lead sponsor	University of Sao Paulo
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	prevention
Enrollment	15
Start date	26 May 2025
Primary completion	5 March 2026
Estimated completion	31 December 2026
Sites	1 location across Brazil

Drugs / interventions tested

Echium oil
Ahiflower oil
EPA capsules

Conditions studied

Cardiovascular (CV) Risk — all drugs for Cardiovascular (CV) Risk →
Atheroscleroses — all drugs for Atheroscleroses →
Inflamation — all drugs for Inflamation →
Omega 3 Fatty Acids — all drugs for Omega 3 Fatty Acids →

Sponsor

University of Sao Paulo

Who can join

Adults 18 to 30, any sex, with Cardiovascular (CV) Risk or Atheroscleroses. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This randomized, single-blind, crossover clinical trial aims to evaluate Echium oil and Ahiflower® oil as sustainable, plant-based alternatives to marine oils for omega-3 supplementation. Although fish oil is the primary dietary source of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), its use as a dietary supplementation presents several drawbacks, including high cost, potential contamination, limited global supply, and sustainability concerns. Echium and Ahiflower oils are naturally rich in stearidonic acid (SDA), a metabolic intermediate that bypasses the rate-limiting Δ6-desaturase step in the omega-3 pathway, potentially enhancing the conversion to EPA. Fifteen participants will undergo three 8-week intervention phases-Echium oil (15 g/day), Ahiflower oil (15 g/day), or EPA capsules (2.34 g/day)-separated by four-week washout periods. Blood samples will be collected before and after each phase to measure fatty acid profiles in plasma, plasma fractions, and erythrocytes using GC-MS. Anthropometric and biochemical parameters will also be assessed. The study seeks to determine whether SDA-rich plant oils can effectively increase EPA levels in humans and potentially reduce the reliance on marine oils for cardiovascular health benefits.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

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Other University of Sao Paulo trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07289919 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Sao Paulo
Last refreshed: 17 December 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07289919.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing