NCT07288411 is a NA clinical trial of nVNS Treatment in TMD, sponsored by Arpana Church.

Who is sponsoring NCT07288411?

NCT07288411 is sponsored by Arpana Church.

What drugs are being tested in NCT07288411?

Interventions in NCT07288411: nVNS Treatment.

What condition does NCT07288411 study?

NCT07288411 studies TMD, Temporomandibular Disorders (TMDs).

Is NCT07288411 still recruiting?

NCT07288411 is currently not yet recruiting. Last updated 17 March 2026.

Last reviewed 2026-03-17 · How we verify

NCT07288411

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Vagus Nerve Stimulation on Temporomandibular Disorders.

Not yet recruiting NA Last updated 17 March 2026

What this trial tests

NA trial testing nVNS Treatment in TMD in 10 participants. Not yet recruiting.

Timeline

1 June 2026

Primary endpoint
31 December 2026

31 December 2026

Quick facts

Lead sponsor	Arpana Church
Phase	NA
Status	Not yet recruiting
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	10
Start date	1 June 2026
Primary completion	31 December 2026
Estimated completion	31 December 2026

Drugs / interventions tested

nVNS Treatment

Conditions studied

TMD — all drugs for TMD →
Temporomandibular Disorders (TMDs) — all drugs for Temporomandibular Disorders (TMDs) →

Sponsor

Arpana Church

Who can join

Adults 18 to 50, female only, with TMD or Temporomandibular Disorders (TMDs). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study aims to examine the effects of transcutaneous non-invasive vagus nerve stimulation (nVNS) on symptoms and brain mechanisms in premenopausal women with temporomandibular disorders (TMD). Non-invasive vagus nerve stimulation (nVNS) is the most well researched and possibly the most effective non-invasive neuromodulation treatment for chronic pain conditions that targets the brain-gut-microbiome (BGM) axis. Participants will be asked to come in for 2 in-clinic visits, at baseline and post treatment. Participants will also be asked to come in 2x/week for 8 consecutive weeks to receive the nVNS treatment. The in-clinic visits will include physical measures, blood draw, saliva sample, and brain MRI. Participants will be asked to collect a stool sample at home and answer online questionnaires regarding, mood, pain, and health behaviors at home, prior to the in-clinic appointments.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for TMD

Currently open trials in the same condition.

NCT07304557 — Effects Exercises in Temporomandibular Joint Disorders on Pain, Joint and Tongue Functions · NA · recruiting
NCT06948162 — Exploration of the Utility of Dental-dedicated MRI for Dentistry · recruiting
NCT07351812 — Two Treatment Modalities for Myogenous Temporomandibular Disorders · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07288411 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Arpana Church
Last refreshed: 17 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07288411.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing