NCT07287462: Neuro_SURGEM

Cranio-spinal Neurosurgical Approaches

Not yet recruiting Last updated 17 December 2025

What this trial tests

trial testing Standardized cranio-spinal neurosurgical approaches performed on donated cadaveric specimens to assess surgical exposure, feasibility, anatomical variation, and selected new techniques. in Minimally Invasive Techniques in 35 participants. Not yet recruiting.

Timeline

30 December 2025

Primary endpoint
30 June 2028

30 July 2028

Quick facts

Lead sponsor	Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Status	Not yet recruiting
Study type	OBSERVATIONAL
Enrollment	35
Start date	30 December 2025
Primary completion	30 June 2028
Estimated completion	30 July 2028

Drugs / interventions tested

• Standardized cranio-spinal neurosurgical approaches performed on donated cadaveric specimens to assess surgical exposure, feasibility, anatomical variation, and selected new techniques.

Conditions studied

• Minimally Invasive Techniques — all drugs for Minimally Invasive Techniques →
• Neurosurgical Procedures — all drugs for Neurosurgical Procedures →
• Cadaveric Training — all drugs for Cadaveric Training →

Sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Who can join

18 and older, any sex, with Minimally Invasive Techniques or Neurosurgical Procedures. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this observational study is to learn how different cranio-spinal surgical approaches work and how much anatomical exposure each technique provides in donated human cadaver specimens. The study also aims to understand anatomical variations and to evaluate new surgical techniques and tools that may improve neurosurgical training and practice.

The main questions it aims to answer are:

* How much surgical exposure area and volume of work does each cranio-spinal approach allow?
* How do anatomical variations influence the effectiveness and feasibility of different approaches? Researchers will also compare results obtained using different surgical visualization methods (such as the surgical microscope approach or macroscopic evaluation) to see if any method improves visibility or operative efficiency.

Cadaveric specimens will undergo:

* Step-by-step cranio-spinal surgical approaches performed by trained neurosurgeons.
* Quantitative measurements of exposed anatomical areas using imaging software (BrainChop).
* Assessment of operative time, perceived difficulty by surgeons, and visibility of target anatomical structures.
* Testing of new surgical instruments or techniques when applicable, without involving any drugs or medical devices.

This study follows Italian regulations on post-mortem body donation for scientific research (Law No. 10/2020) and is conducted at a single research center recognized as an IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico-Scientific Institute for Hospitalization and Care).

Publications & conference data

No peer-reviewed publications indexed yet for this trial.